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Dupilumab is associated with significantly reduced severe exacerbation rates in patients with late-onset asthma with or without fixed airway obstruction

Dupilumab Cuts Exacerbations in Late-Onset Asthma

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Lung function improved at weeks 12 and 52 in patients with, without fixed airway obstruction
The FRAX fracture risk tool can stratify fracture risk equally well among women receiving aromatase inhibitor therapy for breast cancer and nonusers of the therapy

Fracture Risk Tool Useful for Women on Aromatase Inhibitors

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Findings question considering aromatase inhibitors a 'secondary cause of osteoporosis'
U.S. health care organizations lost nearly $454 million due to clinical drug diversion in 2018

Clinical Drug Diversion Costly to Health Care Organizations

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Report finds 47.2 million doses lost due to health care worker misuse and theft in 2018
For patients with rheumatoid arthritis undergoing arthroplasty

Postoperative Infection Rate Similar Across Biologics in RA

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Glucocorticoid use ups risk for hospitalized infection, prosthetic joint infection after arthroplasty
For patients with mild asthma with a low sputum eosinophil level

Mometasone, Tiotropium Do Not Top Placebo in Mild Asthma

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And budesonide-formoterol superior to albuterol for prevention of asthma exacerbations
The risk for spontaneous abortion is increased among early pregnancies with incident exposure to benzodiazepines

Risk for Miscarriage Up With Benzodiazepine Use in Early Pregnancy

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Risk similar for exposure to short-acting, long-acting benzodiazepines during early pregnancy
The selective Bruton's tyrosine kinase inhibitor evobrutinib at a dose of 75 mg once daily is associated with fewer enhancing lesions during weeks 12 through 24 among patients with relapsing multiple sclerosis

AAN: Oral BTK Inhibitor Superior to Placebo in Multiple Sclerosis

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Fewer enhancing lesions seen in weeks 12 to 24 for 75 mg evobrutinib once daily versus placebo
A prognostic model can predict the risk for seizures in pregnant women with epilepsy on medication

Tool Predicts Seizure Risk During, After Pregnancy

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Risk for seizures predicted for pregnant women with epilepsy on medication
When pharmacies close

Heart Patients at Risk When Pharmacies Close

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Study shows link between pharmacy closures and medication noncompliance among patients with CVD
Fournier gangrene is a safety concern for adults with diabetes receiving treatment with sodium-glucose cotransporter-2 inhibitors

Fournier Gangrene Is Safety Concern With SGLT2 Inhibitors

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FDA identified 55 cases of FG in patients on SGLT2 inhibitors from March 2013 through January 2019