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For patients with mild-to-moderate Alzheimer disease

Nilvadipine Increases Cerebral Blood Flow in the Hippocampus

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CBF did not significantly change in posterior cingulate cortex, other regions of interest in Alzheimer disease

American Diabetes Association, June 7-11

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The American Diabetes Association 79th Scientific Sessions The annual meeting of the American Diabetes Association was held from June 7 to 11 in...
Three large drug makers have launched a legal challenge against the Trump administration's rule requiring the prices of drugs to be included in television ads.

Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads

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Lawsuit against the rule filed Friday by Merck, Eli Lilly, and Amgen
Compared with insulin glargine

ADA: Combo Injectable Controls Blood Glucose Longer in T2DM

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Findings seen for initial injectable therapy with insulin degludec plus liraglutide versus insulin glargine
There is an increased risk for behavioral problems in children of mothers with epilepsy who take common antiepileptic drugs during pregnancy

Prenatal Antiepileptic Rx Exposure Ups Risk for Behavioral Issues

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Findings seen among Dutch children exposed to one of four common antiepileptic drugs in utero
A 14-day course of an Fc receptor-nonbinding anti-CD3 monoclonal antibody

ADA: Teplizumab Can Delay T1DM Progression in Those at Risk

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Median time to type 1 diabetes diagnosis 48.4 months with teplizumab and 24.4 months with placebo
For left ventricular assist device recipients

PDE5i Use Linked to Post-LVAD Right Heart Failure Events

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Incidence of severe early right heart failure higher among patients on preimplant PDE5i than controls
Valproic acid and topiramate are confirmed teratogens

Study Confirms Teratogenicity of Valproic Acid, Topiramate

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Eight specific types of major congenital malformations associated with prenatal exposure to valproic acid
Dulaglutide is associated with a reduction in cardiovascular events and renal outcomes among patients with type 2 diabetes

ADA: Dulaglutide Tied to Decline in Cardiovascular Events in T2DM

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Second study shows reduction in renal outcomes with dulaglutide in type 2 diabetes
The U.S. Preventive Services Task Force recommends preexposure prophylaxis and HIV screening for prevention of HIV infection. These recommendations form the basis of two final recommendation statements published online June 11 in the Journal of the American Medical Association.

USPSTF Issues Recommendations on HIV Screening, Prevention

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Recommendations support PrEP for those at high HIV risk, screening for teens, adults, in pregnancy