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Two experimental Ebola treatments have worked so well in the Democratic Republic of Congo outbreak that they will be offered to all patients

New Ebola Drugs Highly Effective, Might Shorten Outbreak in Africa

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The treatments, REGN-EB3 and mAb-114, are both monoclonal antibodies
Misuse of prescription drugs is common among high school students

Prescription Drug Misuse Common in High Schoolers

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44 percent of high school seniors who misuse prescription drugs have multiple drug sources
Spending associated with essential medicines grew substantially from 2011 to 2015 for Medicare Part D beneficiaries

Medicare Spending on Essential Medicines Up 116 Percent From 2011 to 2015

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22 percent of increased total spending due to higher per-unit cost of existing drugs
For women with intrahepatic cholestasis of pregnancy

Common Therapy for Obstetric Cholestasis Found Ineffective

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Treatment with ursodeoxycholic acid versus placebo yielded no significant difference in outcome
Sotagliflozin

Addition of Sotagliflozin for T1DM Alters Renal Hemodynamics

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Addition of SOTA tied to reductions in estimated glomerular filtration rate, blood pressure
From 2012 to 2018

2012 to 2018 Saw Substantial Rise in Naloxone Dispensing

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Regional variation in naloxone dispensing considerable; rates lowest in most rural counties
Efpeglenatide once weekly leads to dose-dependent reductions in glucose and body weight in patients with early type 2 diabetes

Study Explores Dose Ranges for Efpeglenatide in Early T2DM

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Safety profile consistent with other long-acting glucagon-like peptide 1 receptor agonists
Brand-brand competition in the U.S. pharmaceutical market has not lowered drug list prices

Brand-Brand Competition Has Not Cut Prices in Pharma Market

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Review shows evidence that brand-brand competition was mediated by quality of competing drugs
For adolescents with perinatally acquired HIV

Compliance With Meds Falters With Age in Youth Born With HIV

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Prevalence of nonadherence increased from preadolescence to late adolescence/young adulthood
For patients with previously untreated chronic lymphocytic leukemia

Ibrutinib-Rituximab Beats Chemoimmunotherapy for CLL

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Progression-free, overall survival improved in the ibrutinib-rituximab group at three years