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For patients with type 2 diabetes at low cardiovascular risk

Comparative Effectiveness of Treatments Explored in T2DM

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Greatest drop in HbA1c for insulin, specific glucagon-like peptide-1 receptor agonist added to metformin
Gilead Sciences

COVID-19 Drug Remdesivir Could Cost Up to $3,120 Per Patient

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In the U.S., government programs, additional Gilead assistance should mean all patients have access to the drug
Hospitalized patients with COVID-19 receiving colchicine have significantly improved time to clinical deterioration

Colchicine May Improve Time to Clinical Deterioration in COVID-19

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Significant improvement seen in time to clinical deterioration for hospitalized patients with COVID-19
Triple therapy

Triple Inhaled Therapy Aids in Moderate-to-Very Severe COPD

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Benefit seen for twice-daily triple inhaled therapy with glucocorticoid, glycopyrrolate, formoterol
Inhibition of sclerostin with romosozumab may increase cardiovascular risk

Inhibition of Sclerostin May Increase Cardiovascular Risk

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SOST genetic variants linked to lower risk for fracture and osteoporosis but higher risk for MI, major CV AEs
Allopurinol does not affect estimated glomerular filtration rate in patients with chronic kidney disease and does not result in a clinically meaningful benefit in kidney outcomes from serum urate reduction among patients with type 1 diabetes and early-to-moderate diabetic kidney disease

Allopurinol Does Not Affect eGFR in Chronic Kidney Disease

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And, serum urate lowering with allopurinol did not affect GFR in T1DM and diabetic kidney disease
Use of tocilizumab to target cytokine release syndrome seems beneficial for patients with COVID-19

Tocilizumab Shows Promise for Treatment of COVID-19

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Tocilizumab improves oxygenation and inflammatory biomarkers, may improve survival in severe disease
In 2015 to 2018

CDC: 10.7 Percent of U.S. Adults Used Rx Pain Meds in 2015 to 2018

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No change found in use of prescription opioids from 2009-2010 to 2017-2018, but increase seen in nonopioid meds
The occurrence of nephrogenic systemic fibrosis appears to be rare after exposure to newer gadolinium-based contrast agents

Nephrogenic Systemic Fibrosis Rare With Newer GBCA Exposure

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Data scant on exposure to gadolinium-based contrast agents for those with acute kidney injury, risk for CKD
For patients with melanoma treated with immune checkpoint inhibitors (ICIs)

Vitamin D May Cut Colitis Risk for Immune Checkpoint Inhibitors

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Odds of developing ICI colitis significantly reduced with vitamin D use in patients with melanoma