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FDA Approves Dupixent for Chronic Spontaneous Urticaria

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Approval granted for adults and children 12 years and older who remain symptomatic despite antihistamine treatment

Many ADHD Medications Lead to Increases in Blood Pressure and Heart Rate

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Increases in hemodynamic signs seen with amphetamines, atomoxetine, lisdexamfetamine, methylphenidate, and viloxazine

Midafternoon Dosing Improves Lung Function in Atopic Asthma

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Improvement seen in nocturnal lung function and overnight suppression of blood eosinophil counts

Flares Occur Frequently in Generalized Pustular Psoriasis

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Frequent treatment alterations of off-label biologics and nonsteroidal systemic agents observed

FDA Approves Self-Injection of Vyvgart Hytrulo

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Approval granted for patients with generalized myasthenia gravis or chronic inflammatory demyelinating polyneuropathy

FDA Approves Combo of Opdivo Plus Yervoy for Advanced Liver Cancer

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The CheckMate-9DW trial showed significant overall survival benefit versus lenvatinib or sorafenib

Breast Surgery Can Be Omitted After Neoadjuvant Systemic Therapy in Select Patients

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Patients with initial nodal metastases and breast pCR on vacuum-assisted biopsy who underwent targeted axillary dissection had axillary pCR

AAN: Tolebrutinib Slows Disability in Nonrelapsing Secondary Progressive MS

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Tolebrutinib treatment associated with 31 percent risk reduction in six-month confirmed disability progression versus placebo

AAN: Tavapadon as Adjunct to Levodopa Ups Daily ON Time in Parkinson Disease

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Significant reduction also seen in change from baseline in daily OFF times versus placebo

Alteplase Increases Frequency of Functional Independence After Posterior Circulation Stroke

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Findings seen in patients with posterior circulation stroke and with no planned thrombectomy who received alteplase 4.5 to 24 hours after stroke onset