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Genomic targeted prostate cancer treatment shows a survival benefit in patients with metastatic castration-resistant prostate cancer

Genomically Targeted Treatment Slows Advanced Prostate Cancer

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Men receiving olaparib versus standard treatment experience delayed disease progression
Patients with COVID-19 who receive hydroxychloroquine have a high risk for corrected QT prolongation

Hydroxychloroquine in COVID-19 Ups Risk for QTc Prolongation

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Concurrent treatment with azithromycin linked to greater changes in corrected QT interval
A minor planned decrease in the upper limit of the reference range for thyroid-stimulating hormone (TSH) resulted in an increase in levothyroxine prescriptions and more TSH measurements

Testing, Prescribing Increase After Change to TSH Reference Range

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Levothyroxine prescriptions, TSH measurements increased after upper limit of normal for TSH lowered
For patients with atherosclerotic cardiovascular disease and low-density lipoprotein cholesterol ≥70 mg/dL or non-high-density cholesterol ≥100 mg/dL despite statin therapy

Evolocumab Does Not Impact Cognition in Atherosclerotic CVD

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Adding evolocumab to maximally tolerated statin therapy did not affect patient-reported cognition
Pharmacologic treatment for type 2 diabetes increased from 2003 to 2016

Diabetes Medication Prescribing Increased 2003 to 2016

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However, authors say there is little evidence that doctors are tailoring treatment for patients
For treatment of retinopathy of prematurity

Low Doses of Bevacizumab Tested for Retinopathy of Prematurity

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Phase 1 study suggests that intravitreous injection of 0.004 mg may be lowest effective dose
Changes to health care have been reported among patients with rheumatic diseases during the COVID-19 pandemic

COVID-19-Linked Changes Reported in Rheumatic Disease Patient Care

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Forty-two percent of patients report change in care in previous two weeks
Malaria drugs touted by some as potential "game changers" against COVID-19 are actually too dangerous for general use

FDA Warns About Treating COVID-19 With Unproven Drugs

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Chloroquine, hydroxychloroquine may trigger potentially fatal heart rhythm problems in COVID-19 patients
Clascoterone cream

Clascoterone Cream Safe, Effective for Acne Treatment

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Clascoterone cream, 1 percent, is a novel topical androgen receptor inhibitor
For patients hospitalized with mild/moderate COVID-19

Lopinavir/Ritonavir, Umifenovir Ineffective for Mild COVID-19

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Rate of positive-to-negative conversion of SARS-CoV-2 did not differ for drug therapy versus standard care