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For adults hospitalized with COVID-19 with lower respiratory tract infection

Remdesivir Beats Placebo for Time to COVID-19 Recovery

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Researchers suggest antiviral agents in combination with other therapeutic approaches may further improve outcomes
The World Health Organization has suspended use of the antimalarial drug hydroxychloroquine in a clinical trial of treatments of COVID-19 after a study revealed that patients taking the drug are at increased risk for death and serious heart problems.

WHO Suspends Testing of Hydroxychloroquine in COVID-19 Patients

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In light of recent findings, hydroxychloroquine arm of WHO global study paused temporarily
The antiobesity medications phentermine and topiramate may help mitigate weight regain after Roux-en-Y gastric bypass surgery

Antiobesity Meds May Curb Weight Regain After RYGB

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Statistical models suggest phentermine, topiramate, combination can slow, prevent weight regain
Clinically important increases in melanoma risk in patients treated with biologic therapy for common inflammatory diseases cannot be ruled out based on current evidence

Melanoma Risk From Biologic Therapy Remains Uncertain

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Systematic literature review and meta-analysis reveal link to increased risk cannot be ruled out
For patients at high risk for or with established cardiovascular disease in primary care

Sex Differences ID’d in Prescription of Cardiovascular Meds

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Women are less likely to be prescribed aspirin, statins, antihypertensive medications, including ACEIs
Hydroxychloroquine does not improve outcomes in COVID-19

Hydroxychloroquine Does Not Improve COVID-19 Pneumonia Outcomes

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Second study shows no benefit versus standard of care in probability of negative conversion by 28 days
Uptake of guideline-directed preventive therapies is lower for patients with stroke and peripheral artery disease compared with those with coronary artery disease

Statin, Aspirin Uptake Low With Peripheral Artery Disease, Stroke

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Authors call for increased awareness of need for treatment with secondary preventive medications
Treating hospitalized COVID-19 patients with hydroxychloroquine

Hydroxychloroquine No Aid for COVID-Related Mortality

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Hydroxychloroquine alone or with azithromycin associated with abnormal electrocardiogram findings
For patients with metastatic urothelial carcinoma

Addition of Atezolizumab May Aid in Metastatic Urothelial Cancer

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Phase 3 trial shows prolonged progression-free survival for atezolizumab plus platinum-based chemo
Interferon-α2b therapy seems to shorten the duration of viral shedding in hospitalized COVID-19 patients

Interferon-α2b May Shorten Viral Shedding Duration in COVID-19

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Duration of elevated blood levels for inflammatory markers IL-6, C-reactive protein also reduced