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A study to assess whether certain approved or experimental drugs are effective against COVID-19 and warrant testing in large clinical trials has been launched by the U.S. National Institutes of Health (NIH).

NIH Launches Trial of Antibody Drugs Against COVID-19

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The phase 2 trial will assess effectiveness of monoclonal antibodies in conjunction with remdesivir
Enrollment in a study testing an experimental antibody therapy against COVID-19 has been paused by independent monitors.

COVID-19 Antibody Treatment Study Paused

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ACTIV-3 study, testing use of an antibody therapy with remdesivir, paused 'out of an abundance of caution'
Evidence-based guidelines successfully reduce postoperative opioid prescribing without increased refill rates

One Size May Not Fit All for Postoperative Opioid Prescribing

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Guidelines reduce postoperative opioid prescribing but may result in inadequate pain control for some
For patients hospitalized with COVID-19

Remdesivir Cuts Time to COVID-19 Recovery

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However, no significant difference in mortality found between remdesivir and placebo groups
The majority of older adults who take multiple medications have never had a comprehensive medication review

Poll: Medication Management Lacking in Older Adults

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Most older adults taking multiple medications have never had a comprehensive medication review
Regeneron Pharmaceuticals Inc. said Wednesday that it is seeking emergency approval from the U.S. Food and Drug Administration for an experimental antibody cocktail given to President Donald Trump shortly after he was diagnosed with COVID-19.

Maker of Antibody Cocktail Trump Took Seeks Emergency Use Authorization

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Although effectiveness has not yet been seen in humans, drug has shown promise in treating mild cases of COVID-19
Lopinavir-ritonavir is not associated with reductions in 28-day mortality or duration of hospital stay among patients admitted to the hospital with COVID-19

Lopinavir-Ritonavir No Benefit in Patients Admitted With COVID-19

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No reductions seen in 28-day mortality or duration of hospital stay in COVID-19 with lopinavir-ritonavir
Eli Lilly and Co. is seeking U.S. approval for emergency use of an experimental antibody therapy for COVID-19.

Company Seeks FDA Emergency Approval for COVID-19 Antibody Therapy

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Request based on partial clinical trial findings suggesting the drug reduces symptoms in mild or moderate COVID-19
For patients with hormone receptor-positive

Abemaciclib Beneficial for HR+, HER2− Early Breast Cancer

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Significant improvements seen in rates of invasive disease-free survival, distant recurrence-free survival
Hydroxychloroquine administered for eight weeks as preexposure prophylaxis has no clinical benefit in hospital-based health care workers exposed to patients with COVID-19

Hydroxychloroquine Not Beneficial for SARS-CoV-2 Preexposure Prophylaxis

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No clinical benefit seen versus placebo for hospital-based health care workers exposed to patients with COVID-19