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Inhibition of interleukin-1β with canakinumab seems to reduce the incidence of total hip replacement/total knee replacement compared with placebo

Canakinumab Explored as Therapy for Large-Joint Osteoarthritis

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Exploratory analysis reveals total hip/knee replacement rate reduced with canakinumab versus placebo
Cost-related prescription nonadherence is highest among younger U.S. women compared with individuals living in 10 other high-income countries

Cost-Related Rx Nonadherence Highest in Young U.S. Women

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One in four women report cost-related nonadherence versus one in seven men
One-third of pharmacists say they do not have enough remdesivir to treat all COVID-19 patients who are eligible for it

Remdesivir Shortages Plague Some Hospitals, Pharmacists Say

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One-third of pharmacists report that they do not have enough remdesivir to treat all eligible patients
Increasing adherence to evidence-based prophylaxis protocols for epidermal growth factor receptor inhibitor-associated rash can reduce interventions and toxicity-associated chemotherapy interruptions

Adherence to Prophylaxis for EGFRi-Linked Rash Beneficial

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Adherence to prophylaxis protocols tied to drop in interventions, toxicity-linked chemo interruptions
Women taking β-blockers for hypertension have an increased risk for developing heart failure when they present to the hospital with acute coronary syndrome

Risk for Heart Failure Increased for Women Taking β-Blockers

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Difference of 4.6 percent found between women and men in rate of heart failure at presentation for ACS
Baloxavir demonstrates postexposure prophylactic efficacy for preventing influenza in household contacts of index patients

Baloxavir Protects Household Contacts From Influenza

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Percentage of patients in whom clinical influenza developed significantly lower in baloxavir group
There is more good news on the effectiveness of the antiviral drug remdesivir against COVID-19

Gilead Presents Additional Data on Efficacy of Remdesivir for COVID-19

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Pharma company says there is further evidence remdesivir may reduce deaths, hasten recovery
For patients with atopic dermatitis and moderate-to-severe pruritus

Nemolizumab Beats Placebo for Reduction of Pruritus in Eczema

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VAS score reduction greater at week 16 for addition of nemolizumab versus placebo to topical agents
A small molecule that disrupts the functions of the HIV capsid protein

Long-Acting Drug Targeting Capsid Protein Promising for HIV

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Reduction of viral load seen nine days after dose; sustained plasma exposure seen for more than six months
From February to March 2020

February to March 2020 Saw Surge in Hydroxychloroquine Rx

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Number of patients receiving hydroxychloroquine, chloroquine prescriptions climbed across the U.S.