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AHA: Polypill, With or Without Aspirin, Reduces Cardiovascular Events

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Significant reductions seen in primary outcome for use of polypill and polypill plus aspirin combination

Triplet Therapy Slows Refractory Multiple Myeloma

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Progression-free survival longer with once-weekly selinexor-containing regimen versus standard bortezomib and dexamethasone

Fluvoxamine Linked to Reduction in Clinical Deterioration in COVID-19

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Findings seen among adult outpatients with SARS-CoV-2 with oxygen saturation of 92 percent or greater

HealthDay Reports: Coronavirus Has Killed Thousands at US Nursing Homes

Nebulized Interferon Beta-1a Promising for COVID-19

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Adults hospitalized for COVID-19 receiving SNG001 versus placebo more likely to show clinical improvement

Arthritis

ACR Previews New Pharmacotherapy Guidelines for RA

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The 2020 Guideline for the Management of Rheumatoid Arthritis updates guidance on drug treatments

ACR: Warfarin Tied to Increased Risk for Knee, Hip Replacement in OA

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Among adults with atrial fibrillation, warfarin use linked to increased odds of knee, hip replacement versus direct oral anticoagulants

AHA: Black Patients Less Likely to Receive Indicated BP Treatment Intensification

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This accounts for about a quarter of the total effect on blood pressure control

Antipsychotic Use Declined in Young Children From 2009 to 2017

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While there was a shift toward evidence-based indications, majority of use remains off-label

ACR: Incidence of COVID-19 Low in Patients With Rheumatic Disease

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73 percent of those with SARS-CoV-2 infection not hospitalized; 11 percent of those hospitalized required ICU admission

Outcomes Mixed After Heart Transplant Policy Change in the U.S.

AHA: Mavacamten May Treat Hypertrophic Cardiomyopathy

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Improvements in cardiac structure, function seen at 30 weeks of treatment with mavacamten versus placebo