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For Rural Youth

Psilocybin Promising for Treating Major Depressive Disorder

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Mean GRID Hamilton Depression Rating Scale scores significantly lower in immediate treatment group

Vosoritide increases bone growth velocity in children with achondroplasia

Vosoritide Aids Bone Growth in Children With Dwarfism

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Compared with placebo, vosoritide increased growth velocity to near-normal annual rate
Finerenone results in a lower risk for chronic kidney disease (CKD) progression in patients with CKD and type 2 diabetes

ASN: Finerenone May Slow Progression in CKD With T2DM

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Risks for chronic kidney disease progression, CV events lower with finerenone versus placebo
In a 2020 guideline from the International Antiviral Society-USA

Recommendations Updated for HIV Treatment, Prevention

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Prompt initiation of antiretroviral therapy advised in those with HIV and detectable viremia
Tocilizumab may be beneficial for adults with COVID-19 admitted to the intensive care unit

Findings Conflicted for Benefit of Tocilizumab in COVID-19

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One trial shows reduction in mortality, but no evidence of efficacy seen in two additional trials
Chemotherapy-free induction and consolidation first-line treatment with dasatinib and blinatumomab is associated with a high incidence of molecular response and survival in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia

Dasatinib + Blinatumomab Active for Ph-Positive ALL in Adults

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Complete remission, overall survival seen in 98, 95 percent of patients in phase 2 study
For moderately ill hospitalized patients with COVID-19

Tocilizumab Does Not Prevent Intubation, Death in COVID-19

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Intubation or death, disease worsening similar for tocilizumab, placebo in hospitalized patients
In 2017 to 2019

CDC: 65.3 Percent of U.S. Women Currently Using Contraceptives

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Female sterilization most common contraceptive method; use declined with higher education
For about 20 percent of patients with neovascular age-related macular degeneration

Anti-VEGF Therapy May Aid Visual Acuity in Some nAMD Patients

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Useful visual acuity preserved for about 20 percent of patients over their average remaining lifetime
Upadacitinib is superior to abatacept for patients with rheumatoid arthritis refractory to biologic disease-modifying antirheumatic drugs

Upadacitinib Tops Abatacept for RA Refractory to DMARDs

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Superior for mean change in composite DAS28-CRP values and remission, but more adverse events seen