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Ivermectin Does Not Speed Symptom Resolution in Mild COVID-19

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No significant improvement seen in median time to resolution of symptoms with ivermectin versus placebo

Semaglutide May Aid Weight Loss in Obese Patients With T2DM

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Estimated change in mean body weight to week 68 was −9.6 percent with semaglutide 2.4 mg versus −3.4 percent with placebo

Terlipressin Bests Placebo in Type 1 Hepatorenal Syndrome

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Terlipressin is more effective for reversal of HRS but is associated with more adverse events and death due to respiratory disorders

Nivolumab Plus Cabozantinib Tops Sunitinib for Renal Cell Carcinoma

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Combination therapy superior with respect to progression-free, overall survival and overall response for first-line treatment of advanced RCC

​IL-6 Receptor Antagonists Benefit Critically Ill With COVID-19​

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Improved outcomes, including more organ support-free days, reduced mortality, seen with tocilizumab, sarilumab

Lenvatinib Plus Pembrolizumab Tops Sunitinib in Advanced RCC

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Progression-free, overall survival significantly longer with combo versus sunitinib for advanced renal cell carcinoma

Relugolix Combo Therapy Beneficial for Fibroid-Related Menorrhagia

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Significantly more women had reduced menstrual bleeding with once-daily relugolix combination therapy versus placebo

Avacopan Noninferior to Prednisone for ANCA-Associated Vasculitis

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Avacopan noninferior to prednisone taper for remission at week 26, superior to prednisone taper for sustained remission at week 52

Enfortumab Vedotin Prolongs Survival in Advanced Urothelial Cancer

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Overall survival longer compared with standard chemo for disease progression following platinum-based chemo and PD-1 or PD-L1 inhibitor

Certain Prostate Drugs Tied to Risk for Parkinson Disease

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Use of glycolysis-enhancing drugs terazosin, doxazosin, or alfuzosin tied to lower risk for developing Parkinson disease than use of tamsulosin