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ACR: Cycling JAK Inhibitors Feasible for Difficult-to-Treat RA

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One-year outcomes similar for cycling JAK inhibitors versus switching to a biologic drug

Sotrovimab Cuts Risk for COVID-19 Progression in High-Risk Patients

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Interim analysis shows lower risk for progression with sotrovimab versus placebo among high-risk patients with mild-to-moderate COVID-19

Itepekimab Bests Placebo for Moderate-to-Severe Asthma

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Incidence of events indicating loss of asthma control lower with itepekimab monotherapy in phase 2, proof-of-concept trial

Merck Allows Poor Nations to Make COVID-19 Pill

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Royalty-free license means companies in 105 countries can sublicense the formulation for antiviral pill molnupiravir and start making it

Adding Interferon Beta-1a to Remdesivir No Better for COVID-19

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For hospitalized adults with COVID-19, time to recovery did not differ with interferon beta-1a plus remdesivir versus remdesivir alone

Belimumab Promising in Combination Therapy for Refractory Lupus

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Lower serum IgG anti-dsDNA antibody levels seen at 52 weeks with belimumab rather than placebo given after rituximab

Lanifibranor Reduces Disease Activity in Nonalcoholic Steatohepatitis

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In phase 2b trial, more patients with active NASH had reduction in disease activity score with lanifibranor versus placebo

Avoid Intensification of Diabetes Meds at Discharge in Older Adults

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For older adults hospitalized with common medical conditions, intensifying diabetes meds at time of discharge shows little benefit

Poisoning Related to Ivermectin Exposure for COVID-19 Described

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In August 2021, 21 calls were received by Oregon Poison Center; six people were hospitalized for toxic effects resulting from use

Psoriatic Arthritis May Up Risk for Preterm Birth, C-Section

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Risk for preterm birth increased with antirheumatic treatment for psoriatic arthritis -- particularly biologics -- during pregnancy