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Trial Begins of Nasal Vaccine for Alzheimer Disease

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Phase 1 trial will include 16 patients ages 60 to 85 years who have early, symptomatic Alzheimer disease but are otherwise in good health

Some Cirrhosis Patients Given Opioid Rx at Outpatient Visits

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Authors say primary care providers in particular need more education on the potential harms of opioids in patients with liver disease

ACR: Risk Factors ID’d for Hydroxychloroquine-Related Retinopathy

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Independent risk factors for HCQ retinopathy include higher doses, longer duration of use, chronic kidney disease, and Asian race

Pfizer Asks FDA for Emergency Approval of Its COVID-19 Antiviral Pill

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Request comes shortly after clinical trial testing the drug was halted early due to overwhelming evidence of its effectiveness

Pfizer COVID-19 Pill to Be Made, Sold Cheaply in 95 Poor Countries

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Countries included in licensing deal mostly in Africa and Asia and account for more than half of the world's population

AHA: Sacubitril/Valsartan No More Beneficial for Chronic Advanced CHF

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No benefit seen versus valsartan for reducing NT-proBNP levels for patients with chronic advanced heart failure and reduced ejection fraction

Pricey Alzheimer Drug Drives Spike in Medicare B Premium: Officials

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New premium will be $170.10 a month, and the $21.60 boost is the biggest increase ever in dollar amount, but not in percentage terms

ASN: Daprodustat Noninferior to ESAs for Treating Anemia in CKD

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Randomized, open-label, phase 3 trials conducted in patients with chronic kidney disease undergoing, not undergoing dialysis

ASN: Chlorthalidone Aids BP Control in Patients With CKD and HTN

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For patients with stage 4 chronic kidney disease and poorly controlled hypertension, addition of low dose of chlorthalidone improves BP control

Oral Nadolol Feasible for the Treatment of Infantile Hemangiomas

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Randomized clinical trial shows oral nadolol noninferior to oral propranolol for treatment of infantile hemangiomas