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Lenvatinib + Pembrolizumab Treats Advanced Endometrial Cancer

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Progression-free, overall survival prolonged with lenvatinib plus pembrolizumab versus treating physician's choice of chemotherapy

Long-Acting Cabotegravir Not Necessarily Cost-Effective for PrEP

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Benefits do not necessarily justify large price difference compared with generic F/TDF for men who have sex with men and transgender women

CV, Cancer Risk Up With Tofacitinib for Rheumatoid Arthritis

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Incidences of major adverse cardiovascular events, cancers higher with tofacitinib versus TNF inhibitor; criteria for noninferiority not met

Remdesivir May Benefit Adults Early in COVID-19 Course

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Real-world data support the use of remdesivir for hospitalized COVID-19 patients receiving no oxygen or low-flow oxygen

Casirivimab + Imdevimab Prevents Progression to Symptomatic COVID-19

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For asymptomatic SARS-CoV-2-positive individuals living with infected household contact, combo cuts incidence of symptomatic COVID-19

Psychotropic Medication Use Linked to Mortality in Cardiac Patients

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Patients with symptoms of anxiety significantly more likely to use psychotropic medications after hospital discharge

Skyrizi Approved for Psoriatic Arthritis

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Approval based on two Phase 3 trials showing more than 50 percent of patients receiving Skyrizi achieved ACR20 response at 24 weeks

FDA May Limit Use of Two COVID-19 Antibody Treatments

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Treatments made by Regeneron and Eli Lilly performed well against earlier variants, but not against omicron

Opioid Overdose Antidote Urged for Schools After Student’s Fentanyl Death

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In response to the incident, Hartford officials pledged to ensure that all city schools are stocked with naloxone

Microbiome Therapeutic Beats Placebo for Recurrent C. difficile

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Investigational oral live microbiome therapeutic superior to placebo in patients with three or more episodes of C. difficile infection