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In Utero Antipsychotic Exposure May Not Up Neurodevelopmental Disorder Risk

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Commonly prescribed antipsychotic medications taken late in pregnancy seem not to meaningfully increase NDD risk in offspring

GLP-1 RA Use May Up Risk for Gallbladder, Biliary Diseases

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GLP-1 RA treatment linked to increased risk, especially in trials for weight loss, and with higher doses and longer duration of use

ED-Initiated Buprenorphine for OUD Often Not Sustained

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Many patients filling buprenorphine prescriptions written by emergency physicians do not subsequently fill prescriptions for the treatment

FDA Advisory Panel Narrowly Votes Against New ALS Drug

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Panelists said they hoped results of a larger study, now underway, would provide more evidence on the drug

Preconception Paternal Metformin Linked to Major Birth Defects

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Genital birth defects, all in boys, more common among metformin-exposed offspring

Use of Medications for Opioid Use Disorder Low

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Past-year use lowest for adolescents and adults aged 50 years and older

FDA Reviewers Give Thumbs Down to New ALS Drug

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Agency said results were 'not persuasive,' citing missing data, mistakes in enlisting patients, other issues

Risk for Ischemic Stroke Up With Antidopaminergic Antiemetic Use

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Increase in risk greatest for metopimazine and metoclopramide; risk for ischemic stroke may be higher in first days of use

AAD: Baricitinib Tops Placebo for Hair Regrowth in Alopecia Areata

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In two phase 3 trials, baricitinib superior to placebo in terms of percentage of patients with a SALT score of 20 or less at week 36

Stakes Are High Ahead of FDA Panel Vote on ALS Drug

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AMX0035 is a combination of two established drug ingredients -- sodium phenylbutyrate and taurursodiol