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Methotrexate Cuts Systolic BP in Rheumatoid Arthritis

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No significant differences seen in diastolic blood pressure, augmentation index, DAS28-CRP

Potentially Inappropriate Medications Linked to Frailty at Cancer Diagnosis

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Each additional Geriatric Oncology-PIM linked to 66 percent increase in odds of being mildly, moderate-to-severely frail at diagnosis

FDA Sends 100 Cease-and-Desist Letters in Crackdown on DTC Drug Advertisements

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Additionally, the agency is eliminating the 'adequate provision' loophole that allowed pharmaceutical companies to list complete risks separately

FDA Approves Inlexzo for Bladder Cancer

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First and only drug releasing system is indicated for patients with BCG-unresponsive non-muscle-invasive bladder cancer seeking bladder preservation

FDA Releases Guidance to Promote Nonopioid Alternatives for Chronic Pain

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New guidance aims to increase nonopioid choices for chronic pain while combating misuse

Half of Women With Hyperemesis Gravidarum Report Major Impacts on Life

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Antiemetic use and outcomes vary widely for this group of patients

WHO Updates List of Essential Medicines to Include GLP-1s

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PD-1/PD-L1 immunotherapies for several metastatic cancers also made the list of essential drugs

2000 to 2023 Saw Rise in Pediatric Exposure to Medications, Supplements

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Overall rate of exposure for children aged 6 to 12 years up by 53.8 percent; >300 percent increase in exposure linked to self-harm, suicidal intent

Baxdrostat Reduces Seated Systolic BP in Uncontrolled, Resistant Hypertension

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Addition of baxdrostat to background therapy results in significantly lower seated systolic blood pressure

FDA Expands Use of Vonvendi for Von Willebrand Disease

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The recombinant treatment is now approved for prophylactic use in adults and for treating bleeding episodes and perioperative use in children