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Tag: Premature Birth

Antenatal corticosteroid therapy is associated with reductions in birth size for infants

Antenatal Corticosteroid Tx Tied to Reduction in Birth Size

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Reduction in birth size seen for infants born preterm, near term, or at term with ACT exposure
Children born by medically assisted reproduction have an increased risk for adverse birth outcomes; however

Adverse Birth Outcomes Up With Medically Assisted Reproduction

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But risks are mainly attributable to factors other than medically assisted reproductive treatment
For extremely preterm infants

Single-Family Rooms May Benefit Very Preterm Infants

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Reduced sepsis, increased breastfeeding rates observed; no difference in neurodevelopment vs. open bay units
Treatment with myo-inositol for up to 10 weeks does not reduce the risk for type 1 retinopathy of prematurity or death versus placebo for premature infants younger than 28 weeks of gestational age

Myo-Inositol Does Not Reduce Retinopathy of Prematurity

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No reduction in risk for type 1 ROP or death with myo-inositol versus placebo in preemies <28 weeks
Both overweight and normal-weight children who were born as extreme preterm infants are at risk for high blood pressure and hypertension

High BP Seen at School Age for Extreme Preterm Infants

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Increased risk of high BP, hypertension seen among both overweight and normal-weight 6- to 7-year-olds
Compared to full-term children

Risk of Sensory Deficits Drops With Rising Gestational Age

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Convulsions, intracranial hemorrhage during the neonatal period up risk of hearing, visual impairment
Early preterm birth is associated with a higher level of attention deficit/hyperactivity disorder symptoms in preschool children after accounting for unmeasured genetic and environmental factors

Early Preterm Birth Linked to Increased ADHD Symptoms

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Association holds after adjustment for unmeasured genetic, environmental factors
Conservative measures to control reflux have limited effect on signs of gastroesophageal reflux in preterm infants

Pharmacologic Tx Should Be Used Sparingly for Reflux in Preemies

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Poor evidence of efficacy and evidence of harm with pharmacologic agents for gastroesophageal reflux
Preterm birth and/or low-birth-weight infants have decreased educational qualifications and rates of employment in adulthood

Preterm Birth Tied to Lower Job Rate, Education in Adulthood

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Preterm/low-birth-weight infants less likely to complete higher education, be employed as adults
During 2014 to 2016

CDC: Preterm Births Increased in United States During 2014-2016

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Numbers reflected increase among late preterm births, especially births occurring at 36 weeks