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Current practice patterns relating to testing and management of thyroid-stimulating hormone during pregnancy are associated with overdiagnosis and overtreatment of hypothyroidism

Thyroid Dysfunction in Pregnancy Overdiagnosed, Overtreated

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In most women with elevated TSH who did not start treatment, repeat measurement was ≤4.00 mIU/L
Higher rates of decidual arteriopathy and other maternal vascular malperfusion features are seen in placentas of women with severe acute respiratory syndrome coronavirus 2

Placental Injury Seen in Pregnant Women With SARS-CoV-2

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Higher rates of decidual arteriopathy, other maternal vascular malperfusion features observed
At the Cedars-Sinai Medical Center in Los Angeles

No SARS-CoV-2 ID’d in Asymptomatic Pregnant Women in Los Angeles

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Among 80 asymptomatic pregnant women admitted to Cedars-Sinai Medical Center, none tested positive
Use of oral fluconazole for treatment of vulvovaginal candidiasis in the first trimester of pregnancy is associated with musculoskeletal malformations

Musculoskeletal Malformations Up With Fluconazole in Pregnancy

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But no increase seen in conotruncal malformations, oral clefts with use of oral fluconazole in first trimester
Fifteen percent of pregnant women with COVID-19 have severe disease

15 Percent of Pregnant Women With COVID-19 Experience Severe Disease

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Nearly all of those with severe disease in case series were overweight or obese before pregnancy
Early diagnosis and treatment of gestational diabetes mellitus in high-risk women improves gestational weight gain

Early Diagnosis of Gestational Diabetes Leads to Less Weight Gain

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Screening high-risk women for GDM in first trimester optimizes gestational weight gain
About 13 percent of women report postpartum depressive symptoms

Prevalence of Postpartum Depressive Symptoms 13.2 Percent

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Overall, 79.1 percent of women reported being asked about depression during prenatal care visits
Risk for preterm delivery is higher in pregnant women who have experienced preeclampsia

Previous Pregnancy Complication Ups Risk for Preterm Delivery

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Any of five complications in a first term delivery may predict subsequent preterm delivery
A cardio-obstetrics team is essential for management of cardiovascular disease during pregnancy

Cardio-Obstetrics Team Key to Managing CVD in Pregnancy

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Cardio-obstetrics team should review maternal cardiovascular risk, obstetric risk, fetal risk, outcomes
The incidence of hypertensive disorders of pregnancy is underestimated when assessed on a per-pregnancy basis and confers a significant increase in risks for cardiovascular and kidney diseases

Incidence of HTN Disorders of Pregnancy Underestimated

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Women with history of HDP have increased risk for stroke, cardiac arrhythmias, chronic kidney disease