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For couples with early pregnancy loss

No Benefit for Delaying Pregnancy After Early Loss

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Couples with 0- to 3-month interval more likely to achieve live birth versus >3 months
Between 2000 and 2009

Newborn Abstinence Sx Up, Tied to Increasing Prenatal Opioid Use

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~14 to 22 percent of pregnant women in the United States are prescribed opioids
Gestational exposure to paroxetine in the first trimester is associated with increased risk of major congenital malformations and major cardiac malformations

Review: Paroxetine Use in Pregnancy Tied to Malformations

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Increased risk of any major congenital malformations, major cardiac malformations
Polyhydramnios with normal prenatal detailed ultrasound examination is associated with increased risk for adverse outcomes

Polyhydramnios With Normal U/S Linked to Adverse Outcomes

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Higher rate of fetal malformation, genetic syndromes, neurologic disorders, developmental delay
Women with peripartum cardiomyopathy have a prevalence of truncating variants similar to that seen in patients with dilated cardiomyopathy

Truncating Variant Prevalence Up in Peripartum Cardiomyopathy

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Prevalence of 15 percent, similar to that seen in patients with dilated cardiomyopathy
A sFlt-1:PlGF ratio of 38 or lower appears to help rule out preeclampsia in women in whom the syndrome is suspected clinically

Blood Test May Help Rule Out Preeclampsia in Short Term

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Could help predict whether preeclampsia would be diagnosed in the next week
Use of oral fluconazole in pregnancy is associated with increased risk of spontaneous abortion

Oral Fluconazole Exposure Linked to Spontaneous Abortion Risk

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Exposure in pregnancy linked to significantly increased risk of spontaneous abortion
Third-trimester screening for alloimmunization in Rhesus c-negative women improves detection and treatment of hemolytic disease of the fetus and newborn

Third-Trimester Screen Detects Late Alloimmunization

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Detection through additional screening facilitates timely treatment
Metformin reduces soluble fms-like tyrosine kinase 1 and soluble endoglin secretion from primary human tissues

Metformin Looks Promising in the Treatment of Preeclampsia

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Reduces sFlt-1 and sENG secretion from primary human tissues; reduces endothelial dysfunction
The number of births in the United States increased in 2014

CDC: Number of U.S. Births Up to 3.9 Million in 2014

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Decrease in rate of teenage pregnancies, and in birth rates for women in early 20s