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Attention to preoperative stress in adolescents undergoing scoliosis surgery may reduce levels of postoperative pain as well as anxiety and social and attention problems in the recovery period

Pre-Op Stress Tied to Post-Op Pain, Anxiety in Scoliosis Patients

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In adolescents undergoing scoliosis surgery, anxiety and depression higher before procedure
The American Pain Society has issued recommendations on the management of postoperative pain. The clinical practice guideline was published in the February issue of the Journal of Pain.

American Pain Society Releases Guideline on Postoperative Pain

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Care plan should be tailored to the individual and type of surgical procedure involved
Functional magnetic resonance imaging with central sensitization can be used in early human drug development

Functional Imaging Beneficial for Analgesic Drug Development

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Functional magnetic resonance imaging with central sensitization beneficial for selecting analgesics
Subcutaneous botulinum toxin type A injections appear to safely and effectively reduce chronic neuropathic pain in patients with spinal cord injury

Botox May Reduce Chronic Neuropathic Pain

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Findings in small study of patients with spinal cord injury-associated pain
Taking prescription opioids doesn't improve movement or reduce disability for patients with neuropathic pain

Opioids Don’t Ease Disability in Neuropathic Pain

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Medications aren't useful in restoring motion, researchers say
U.S. researchers are challenging a leading theory about the nation's heroin epidemic

Pathway to Heroin Described in NEJM Commentary

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Initial exposure to opioids appears to 'push' potential addicts to heroin
Exposure to opioids is associated with increased likelihood of low testosterone levels

Opioid Exposure Tied to Higher Odds of Low Testosterone Levels

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Increased odds of low testosterone with exposure; increased odds with increasing age, comorbidities
Patients with a nonfatal opioid overdose are almost always prescribed opioids after overdose

After Nonfatal Overdose, Most Patients Prescribed More Opioids

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Cumulative incidence of repeated overdose 17 percent for those receiving high doses after overdose
The top 10 percent of Medicare prescribers account for more than 50 percent of opioid claims

Distribution of Opioid Prescribing ID’d for Different Providers

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Top 10 percent of Medicare prescribers account for 56.7 percent of opioid claims
Mental disorders seem to be associated with chronic pain in adolescents

Mental Disorders Associated With Chronic Pain in Teens

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Most substantial temporal links for affective, anxiety, and behavior disorders prior to chronic pain