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Risk for Dementia, Ischemic Stroke, Mortality Lower With GLP-1 Receptor Agonists in T2D, Obesity

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Significantly lower risks seen for those receiving GLP-1 receptor agonists compared with other antidiabetic drugs

ENDO: Superior Weight Loss Seen With Tirzepatide and Menopausal Hormone Therapy Use

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For postmenopausal women with overweight or obesity receiving tirzepatide, menopausal hormone therapy linked to increased weight loss

Degree of Weight Loss Affects Tirzepatide-Linked Cardiometabolic Risk Improvement

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Linear relationship seen for waist circumference, BP; reduction in HOMA-IR, hemoglobin A1c seen with modest weight reduction

Real-World Weight Loss With Semaglutide, Tirzepatide Less Than That Seen in Clinical Trials

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In real-world cohort, percentage weight reduction at one year was 3.6, 6.8, and 11.9 percent with early and late discontinuation and nondiscontinuation, respectively