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Liver transplantation in childhood is associated with good long-term survival

Good Long-Term Survival After Childhood Liver Transplant

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20-year survival almost 80 percent; over one-third of patients have CKD, altered liver biochemistries
Targeting can enhance accumulation of nanoparticles to graft endothelial cells of human kidneys undergoing ex vivo normothermic machine perfusion

Targeting Ups Nanoparticle Delivery to Graft Endothelial Cells

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Anti-CD31 antibody selectively enhances targeting of NPs to graft ECs of human kidney undergoing NMP
Anti-CD47 monoclonal antibody therapy reduces ischemia-reperfusion injury of renal allografts in an animal transplantation model

Monoclonal Antibodies Cut Ischemia-Reperfusion Injury

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In animal model, anti-CD47 monoclonal antibody group had decease in injury of renal allografts
Nonmedical factors affect racial disparities in kidney transplant wait-listing

ASN: Nonmedical Factors Impact Kidney Transplant Waits

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African-Americans less likely to be wait-listed; higher income positively associated with wait-listing
For organ recipients in Norway

In Norway, Risk of SCC After Organ Transplant Has Fallen

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Standardized incidence ratio peaked in patients who underwent transplantation in 1983-1987 period
For male patients with cirrhosis

Visceral Adipose Tissue Index IDs Risk of HCC in Cirrhosis

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High VATI is also linked to risk of HCC recurrence in males with HCC who underwent liver transplant
Given population obesity trends

Demand for Liver Transplant for NASH Set to Continue Rising

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Increase in obesity prevalence strongly linked to liver transplant waitlist additions nine years later
Graft survival is similar for recipients of kidneys from >80-year-old donors and donors aged ≤60 years

Graft Survival Similar for Kidneys From Octogenarians

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Recipients of biopsy-guided kidneys from >80-year-old donors had significantly shorter waiting times
Characteristics unrelated to allograft quality are associated with later acceptance in the deceased donor kidney match-run

Factors Unrelated to Allograft Quality Tied to Organ Turndown

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Holiday or weekend procurement, shorter donor stature, location of procurement tied to later acceptance

ABO Incompatible Dual Graft Living Donor Liver Transplant Viable

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High graft survival at one-, three-, five-years; no significant difference for ABO compatible, incompatible