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Tag: Organ Transplants

Post-transplant hepatitis C treatment increases access to transplant and reduces waitlist time among hepatitis C-positive patients awaiting kidney transplantation

Post-Transplant Tx Reduces Wait for Kidney in Hep C+ Patients

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Delaying treatment until after transplant doesn't adversely impact kidney allograft or survival
Simultaneous liver-kidney transplant recipients' peripheral blood cells have unique phenotypic and functional characteristics that are associated with donor-specific hypo-alloresponsiveness

Liver-Kidney Recipients Have Donor-Specific Hypo-Responses

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Unique characteristics ID'd in peripheral blood cells of simultaneous liver-kidney transplant recipients
Transplantation of organs from overdose-death donors is associated with similar five-year patient survival and graft survival as organs from trauma-death donors and medical-death donors

Similar Outcomes for Transplant With Overdose-Death Donors

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Outcomes similar for ODD recipients, recipients of organs from trauma-death, medical-death donors
Health care provider awareness of racial disparities in kidney transplant waitlisting is low

Many Providers Unaware of Racial Disparities in Kidney Transplants

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Nurse managers, white providers more likely to be unaware of national racial disparity in waitlisting
There has been a large drop in infection-related deaths following kidney transplantation since the 1990s

Large Drop Seen in Infection-Related Post-Transplant Deaths

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Findings among adults undergoing kidney transplantation in Finland 1990 to 2010
A trained patient navigator helps to increase access to the transplant waitlist for disadvantaged patients with kidney failure who need a longer time to get through the transplant evaluation process

Trained Navigators Help Patients With Kidney Transplant Process

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However, the impact in waitlisting was only seen for disadvantaged after 500 days of follow-up
Direct-acting antiviral prophylaxis is safe and prevents chronic hepatitis C virus (HCV) infection after kidney transplantation from HCV-infected donors to noninfected recipients

Prophylaxis Can Prevent HCV Infection in Kidney Recipients

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With direct-acting antivirals, no adverse events seen when kidneys came from HCV-infected donors
Alternatives to whole liver transplants for children have become safer

Alternatives to Whole Liver Transplants Feasible for Children

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Alternatives helped to improve outcomes 2002 to 2015, indicating new ways to increase organ supply
In children who receive a non-kidney solid organ transplant

Kidney Injury Common After Non-Kidney Transplants in Children

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High risk of AKI in first year after non-kidney solid organ transplant; in turn, increases CKD risk
Racial/ethnic disparities in the receipt of live donor kidney transplantation among first-time kidney transplantation candidates in the United States increased from 1995-1999 to 2010-2014

Racial/Ethnic Disparities Up for Live Donor Kidney Transplant

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Compared to 1995 to 1999, increase in racial/ethnic disparities in receipt of LDKT in 2010 to 2014