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Tag: Opioids

For the first time in three decades

U.S. Drug OD Deaths Fall for First Time in Three Decades

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However, U.S. drug overdose death rate remains about seven times higher than a generation ago
More than one-fourth of patients with acute gout discharged from the emergency department receive an opioid prescription

Opioids Commonly Prescribed in Emergency Department for Gout

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Diabetes, polyarticular gout, prior opioid use tied to increased risk for opioid prescription at discharge
Prepregnancy surgery is associated with elevated neonatal abstinence syndrome risk in future pregnancies

Prepregnancy Surgery Linked to Risk for Neonatal Abstinence Syndrome

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Prescription opioids for postsurgical pain may lead to addiction that affects future pregnancies
For patients undergoing anterior cruciate ligament reconstruction

Prescribing Fewer Tablets Can Cut Post-ACL Surgery Opioid Use

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Prescribing fewer tablets with education session further reduces opioid use
Prenatal opioid exposure is negatively associated with neurocognitive and physical development in offspring from the age of 6 months into school age

Prenatal Opioid Exposure Harms Long-Term Child Development

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Negative effects on cognitive, motor outcomes seen from age 6 months persist to school age
Overall

About 12 Percent With Ankle Sprain Fill Opioid Prescriptions

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Among opioid-naive patients, 8.4 percent of those who filled an initial opioid Rx had persistent use
The vast majority of orthopedic surgeons recommend prescribing a nine-day supply of around-the-clock oxycodone doses following commonly performed orthopedic surgeries

Survey Reveals Gaps in Opioid Rx Patterns of Orthopedic Surgeons

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History of drug misuse, depression did not necessarily diminish hypothetical prescribing rates
In utero exposure to opioids is associated with higher risks for short- and long-term adverse outcomes

In Utero Opioid Exposure Tied to Poor Outcomes Throughout Childhood

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Adverse outcomes seen at birth and in preschool and school-aged children
Patients undergoing partial knee replacement have a reduced risk for venous thromboembolism and opioid use in months 3 to 12 after surgery

VTE Risk Reduced With Partial Knee Replacement

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But risk for five-year revision higher for those undergoing partial versus total knee replacement
Specific patterns of opioid administration to opioid-naive inpatients are associated with risk for long-term use after discharge

Patterns of Inpatient Opioid Use Linked to Long-Term Use

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Outpatient use at 90 days was seen for 5.9 and 3.0 percent of patients with and without inpatient use