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New warnings about the risk for dangerous breathing difficulties when gabapentinoids are used with opioids or by certain patients must now appear on product labels

Gabapentinoids, Opioids Combo Carries Risk for Breathing Problems

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Serious breathing problems can occur in patients who use gabapentinoids with opioids or other CNS depressants
The rate of opioid-related suicides as well as unintentional deaths significantly increased from 2000 to 2017

Opioid-Related Suicides Down, Rate of Unintentional Deaths Up

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Crises of opioid overdose deaths and suicide do not appear closely linked
Coprescription of benzodiazepines and opioid agonist treatment is associated with an increased risk for drug-related poisoning mortality in opioid-dependent individuals

Benzodiazepines With Opioid Agonist Tx May Up Mortality Risk

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Coprescription of z-drugs with OAT also linked to increased risk for drug-related poisoning mortality
The rate of in-hospital births with neonatal abstinence syndrome was 6.7 per 1

Rates of Neonatal Abstinence Syndrome Remain High in U.S.

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Highest rates of neonatal abstinence syndrome seen in lowest income quartile, rural areas, Northeast
Among cancer survivors

Factors Predict Adverse Opioid-Related Outcomes in Cancer Survivors

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Demographic, cancer, and treatment factors can predict outcomes with high level of discrimination
Overall

6.5 Percent of Adults Report Prescription Opioid Analgesic Use

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Percentage using prescription opioid analgesic increased with age; use up for women versus men
Individuals with chronic pain who use daily cannabis have lower odds of using illicit opioids

Daily Cannabis Use Tied to Lower Illicit Opioid Use for Chronic Pain

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Findings based on longitudinal study in Canada of people who use drugs and report chronic pain
Postpartum opioid prescription rates vary widely among hospitals

Postpartum Opioid Prescription Rates Vary Widely by Hospital

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However, providers within the same hospital tend to follow similar prescription patterns
In an expert panel consensus

Dermatologists Issue Consensus Guideline for Opioid Prescribing

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For most uncomplicated procedures, postop pain can be managed with acetaminophen and/or ibuprofen
Prescription opioid use among teens and young adults is higher than expected

~25 Percent of Adolescents, Young Adults Use Rx Opioids

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Focus of prevention should include close friends and family members of teens and young adults