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More than 83 percent of overdose deaths during January to June 2019 involved illicitly manufactured fentanyls

One or More Opioids Involved in ~80 Percent of OD Deaths

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At least one potential opportunity for prevention intervention for 62.7 percent of overdose deaths
An enhanced recovery after surgery program for cesarean delivery is associated with improved outcomes

Enhanced Recovery Approach Aids Cesarean Birth Outcomes

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Benefits of enhanced recovery after surgery program include decreases in opioid use, length of stay, and costs
The TEACH (Targeting Effective Analgesia in Clinics for HIV) intervention is a promising strategy for improving adherence to opioid prescribing guidelines among HIV care providers and their patients on chronic opioid therapy

Program Improves Use of Chronic Opioid Therapy in HIV Care

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TEACH intervention increases adherence to guideline-concordant care for HIV patients with chronic pain
About half of waivered clinicians prescribe buprenorphine for opioid use disorder and most treat at levels below their patient limits

About Half of Waivered Clinicians Prescribe Buprenorphine for OUD

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Percentages much higher for actively prescribing U.S. clinicians with 275 and 100 versus 30 patients
For patients undergoing common orthopedic sports procedures

Nonopioid Pain Protocol Feasible After Sports Orthopedic Surgery

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45 percent of patients did not require opioids for management of postoperative pain
Cancer survivors have higher rates of prescription opioid use but do not have increased rates of prescription opioid misuse compared with those without a history of cancer

Rates of Prescription Opioid Use Higher in Cancer Survivors

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Cancer survivors have similar rates of prescription opioid misuse versus those without cancer
There has been a dramatic increase in overdose fatalities involving illicit opioids

Shift Occurring in Deadly Overdoses

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Rx opioid prescriptions down; illicit drugs are dominant cause of lethal drug overdoses
Preoperative opioid and sedative use are risk factors for morbidity and mortality following colorectal resections

GI Surgical Outcomes Worse With Preop Use of Opioids, Sedatives

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Findings seen in patients undergoing colorectal resection for nontrauma reasons
Persistent opioid use is a common concern after cardiac surgery

Persistent Opioid Use Seen in ~10 Percent of Patients After Cardiac Surgery

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Higher opioid dosage prescribed at discharge associated with increased risk for new persistent use
In 2015 to 2018

CDC: 10.7 Percent of U.S. Adults Used Rx Pain Meds in 2015 to 2018

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No change found in use of prescription opioids from 2009-2010 to 2017-2018, but increase seen in nonopioid meds