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The role of weight-loss surgery for obesity is addressed in a Grand Rounds Discussion published in the June 6 issue of the Annals of Internal Medicine.

Doctors Discuss Role of Weight-Loss Surgery in Obesity

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Grand rounds discussion focuses on 64-year-old with morbid obesity, obesity-related conditions
Non-shivering thermogenesis can transform storage adipose tissues into metabolically active tissue

Non-Shivering Thermogenesis Can Activate Metabolic Pathways

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Non-shivering thermogenesis results in activation and expansion of brown and beige adipose tissue
Excess weight is associated with increased costs across health care settings

Excess Weight Increases Costs Across Health Care Settings

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Percentage increases in costs associated with obesity were highest for medications, higher for women
For obese adults

Breaking Up Sedentary Time With Upper Body Activity Beneficial

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Short bouts of arm ergometry linked to reductions in mean blood glucose, insulin iAUC in obese individuals
Overweight or obesity in youth may have long-lasting repercussions for psychological health

Overweight in Childhood May Up Lifetime Risk of Depression

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Risk four times greater if individuals are also overweight as adults, researchers say
Individuals with metabolically healthy obesity still have a higher risk of cardiovascular disease than normal-weight people

‘Healthy’ Obese Still at Higher Risk of Cardiovascular Disease

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Study of 3.5 million people shows 'healthy' obese at higher risk than the general population
Selective activation of estrogen receptor α activation function-1 prevents obesity

Activation of Estrogen Receptor α-AF1 May Target Adiposity

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ERα-AF1 agonist tamoxifen could reduce food intake and prevent adiposity, insulin resistance, steatosis
A new type of "balloon-in-a-pill" may offer a nonsurgical way for obese people to lose weight -- and get healthier

DDW: Bariatric Balloon Capsule Shows Promise for Weight Loss

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New capsule requires no endoscope; balloon is deflated, then excreted naturally
For overweight and obese adults with type 2 diabetes

Linear Association for Weight Loss, HbA1c Reduction in T2DM

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Data from trials show weight loss is associated with HbA1c reduction in dose-dependent manner
Obesity and sex are differential predictors of acute remission for commonly used antidepressant medications

Obesity, Sex Predict Remission for Antidepressant Medications

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Females, but not males, with higher BMI more likely to remit, regardless of medication type