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Tag: Muscle Problems

Nusinersen is associated with significant and clinically meaningful improvement in motor function among children with later-onset spinal muscular atrophy

Nusinersen Beneficial in Later-Onset Spinal Muscular Atrophy

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Significant improvement in motor function compared with sham procedure among children with SMA
The prevalence of work-related musculoskeletal disorders appears to be high for at-risk physicians

Higher Risk of Musculoskeletal Disorders in Some Physicians

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Increasing risk for work-related musculoskeletal disorders, particularly in procedural specialists
New classification criteria have been developed for idiopathic inflammatory myopathies

Criteria Developed for Idiopathic Inflammatory Myopathies

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Classification criteria developed from rheumatology, dermatology, neurology, pediatric clinic data
Gene replacement therapy is beneficial in spinal muscular atrophy type 1

Gene Replacement Tx Beneficial in Spinal Muscular Atrophy

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And nusinersen improves motor-milestone response for infants with spinal muscular atrophy
Higher levels of echo intensity on ultrasound are associated with lower levels of muscle strength and greater frailty in the elderly

Ultrasound Echo Intensity Is Potential Frailty Biomarker

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High levels of echo intensity associated with lower muscle strength in the elderly
Ultrasonography findings seem to correlate well with the disease activity of idiopathic inflammatory myopathies

Ultrasound Findings Correlate With Inflammatory Myopathies

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While there is not a single ultrasound pattern, findings tied to disease activity
High blood levels of active vitamin D may increase muscle strength

Increased Active Vitamin D May Help Optimize Muscle Strength

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Findings for serum 1,25-dihydroxyvitamin D3 (1α,25[OH]2D3)
Patients with sustained or newly developed cancer cachexia at six and 12 months after initial treatment for advanced head and neck squamous cell carcinoma are at higher risk of cancer recurrences

Cancer Cachexia Associated With Poor Outcomes

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Findings at six and 12 months after treatment for advanced head and neck cancer
Use of complementary health approaches is significantly higher for U.S. adults with musculoskeletal pain disorders

CDC: Complementary Health Use Up With Musculoskeletal Pain

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Over 41 percent of U.S. adults with musculoskeletal pain disorders use complementary health approach
Parity is associated with increased fiber length in the more proximal coccygeus and iliococcygeus pelvic floor muscles

Potential Mechanism ID’d for Impact of Parity on Pelvic Floor

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Parity tied to increased fiber length in more proximal coccygeus, iliococcygeus pelvic floor muscles