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Tag: Muscle Problems

Low muscle mass is associated with all-cause and cardiovascular mortality risk in the elderly

Low Muscle Mass in the Arms, Legs Tied to Mortality in Elderly

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Muscle mass more predictive of mortality than visceral fat, total fat in older women
A tool has been developed that can improve standardization and transparency when describing cell therapies

Experts Develop Standardized Tool for Describing Cell Therapies

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Consensus reached on contents of DOSES tool for improving standardization and transparency
For patients with type 2 diabetes

Poor Glycemic Control Linked to Sarcopenia in T2DM

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Correlation independent of major covariates including anthropometric factors and diabetes duration
The burden of musculoskeletal diseases increased significantly worldwide between 2000 and 2015

Global Burden of Musculoskeletal Diseases on the Rise

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Significant increases seen worldwide, but burden highest in Europe
Limited evidence suggests that nusinersen treatment provides long-term benefits for children with later-onset spinal muscular atrophy

Nusinersen Promising for Later-Onset Spinal Muscular Atrophy

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Phase 1/2 studies reveal long-term improvement in motor function for children with SMA type II and III
ZRT- and IRT-like protein 14 upregulation in skeletal muscles may play a role in cancer-related muscle loss

Excess Zinc in Muscles May Drive Cancer-Related Wasting

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ZIP14 may be a therapeutic target for its treatment
In a case report published online June 18 in BMJ Case Reports

Tattoo-Linked Complications ID’d in Immunosuppressed Female

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Inflammatory myopathy identified in woman with cystic fibrosis on long-term immunosuppressants
For infants with type 1 spinal muscular atrophy who have two copies of the survival motor neuron (SMN) 2 gene

AAN: New Drug May Help Infants With Spinal Muscular Atrophy

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RG7916 increases survival motor neuron protein level, with 6.5-fold increase noted with highest dose
For infants with type 1 spinal muscular atrophy who have two copies of the survival motor neuron (SMN) 2 gene

AAN: New Drug May Help Infants With Spinal Muscular Atrophy

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RG7916 increases survival motor neuron protein level, with 6.5-fold increase noted with highest dose
Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle

Young Adults With T1DM Show Muscle Metabolic Deficiencies

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Lower mitochondrial oxidative capacity in skeletal muscle of physically active young adults with T1DM