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Tag: Multiple Sclerosis

Early Treatment of Demyelination Events Cuts Long-Term Disability in MS

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Reduced risk for reaching EDSS 3.0, secondary progressive MS, sustained disease progression seen with very early treatment

Genes Identified in Association With Multiple Sclerosis Severity

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Significant association identified with rs10191329 in the DYSF-ZNF638 locus, with risk allele shortening time to needing walking aid

Pro-Inflammatory Diet Linked to Worsening Relapse Rate in MS

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Association seen between energy adjusted dietary inflammatory index score and fluid-attenuated inversion recovery lesion volume

Rituximab Not Noninferior to Ocrelizumab for Relapsing-Remitting MS

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Cumulative hazard of relapses higher among patients treated with rituximab versus ocrelizumab

Whites Have Highest Prevalence of Multiple Sclerosis in the United States

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Highest prevalence seen in those aged 45 to 64 years; prevalence also increased with each degree of latitude

AAN: Teriflunomide Reduces Clinical Events in Radiologically Isolated Syndrome

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Significant reduction seen in clinical events with teriflunomide; nonsignificant reduction noted in Gd+ lesions, new or enlarging T2 lesions

Sleep Disorders Contribute to Cognitive Decline in Multiple Sclerosis

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Insomnia, sleep apnea explain roughly 10 to 34 percent of the relationship between multiple sclerosis and cognitive dysfunction

MS Relapse Rate Not Increased After Fertility Treatments

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Mean annualized relapse rate not different before versus after controlled ovarian stimulation

AAN: Mediterranean Diet Score Linked to Cognition in MS

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Higher MEDAS score independently predicted lower risk for cognitive impairment; link stronger for those with progressive disease

Evidence Found of Causal Link for Multisite Chronic Pain and MS, RA

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Association with multiple sclerosis and rheumatoid arthritis may be partially mediated by body mass index