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Tag: Multiple Sclerosis

For patients with primary progressive multiple sclerosis

Ocrelizumab May Help Preserve Hand, Arm Function in PPMS

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Ocrelizumab reduces risk for more severe progression
Rates of multiple sclerosis relapse decrease during pregnancy but increase postpartum

MS Relapse Drops During Pregnancy but Rises After

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Disease-modifying drug use uncommon year before pregnancy and further drops during pregnancy
The rate and frequency of relapse vary for patients with multiple sclerosis

Many Patients Do Not Engage Health Care Provider During MS Relapse

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Only half of patients reported always engaging health care providers
Cannabinoids may be mildly effective at treating spasticity

Cannabinoids Mildly Effective for Treating MS Symptoms in Adults

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Review shows limited effectiveness for aiding spasticity, pain, bladder dysfunction
Older individuals with multiple sclerosis report less severe depressive symptoms and better physical quality of life

Lower Levels of Depression, Higher QOL for Older MS Patients

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Individuals aged 55 to 65 years have less severe depressive symptoms, better physical QOL
Brain iron at quantitative magnetic resonance imaging is associated with disability in multiple sclerosis

Brain Iron on MRI Linked to Disability in Multiple Sclerosis

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Lower thalamic susceptibility, higher susceptibility of the globus pallidus linked to clinical disability
Among pediatric patients with relapsing multiple sclerosis

Fingolimod Cuts Multiple Sclerosis Relapses in Pediatric Patients

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Compared with interferon beta-1a, less lesion accumulation seen on MRI but more adverse events
In patients with progressive multiple sclerosis

Ibudilast Appears to Slow Brain Atrophy Progression in MS

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In phase 2 randomized trial, 2.5 ml less brain-tissue loss with ibudilast than with placebo over 96 weeks
The combination of genetics and exposure to organic solvents in paints and varnishes increases the risk of multiple sclerosis

Organic Solvents + Genetics May Increase Risk of Multiple Sclerosis

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Finding of susceptibility seen regardless of smoking status
Brain volume loss has nonlinear dynamics and limited reproducibility as a marker of therapeutic response in multiple sclerosis

Dynamics of Brain Volume Loss Vary With MS Progression

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Limited reproducibility of estimates seen using different imaging methods