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Tag: Multiple Sclerosis

Elevated plasma neurofilament light chain levels are associated with an increased risk for reaching sustained disability worsening in multiple sclerosis

Plasma NfL Level Tied to Risk for Disability in Multiple Sclerosis

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High pNfL levels linked to increased adjusted rates of Expanded Disability Status Scale worsening
For multiple sclerosis patients with clinically isolated syndrome

Low Vitamin D, Smoking Predict Worse Cognitive Function in MS

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Higher vitamin D predicted better cognitive performance, while smoking predicted worse performance
A new risk score is capable of predicting long-term multiple sclerosis progression

Risk Score Can Predict Long-Term Multiple Sclerosis Progression

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Secondary progression score based on five clinical risk factors
Greater genetic predisposition for multiple sclerosis is associated with altered brain white matter development at an early age

Brain Changes From Multiple Sclerosis May Occur in Preteens

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Greater genetic predisposition for MS tied to imaging-observable changes in white matter in preteens
Features extracted from a multisensor correlate strongly with physician- and patient-reported disability outcomes in multiple sclerosis

Multisensor Data Can Assess MS-Related Limb Dysfunction

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Extracted features from three sensors correlate with physician-rated, patient-reported disability status
Cannabis use is common among multiple sclerosis patients with spasticity

Patients Report Cannabis Eases Spasticity in Multiple Sclerosis

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More than one-third of MS patients with spasticity report current cannabis use
Age of onset for disease is an important factor affecting clinical outcomes across the life span in patients receiving disease-modifying therapy for multiple sclerosis

Age of Onset May Affect Clinical Outcomes for MS Patients on DMT

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Age-dependent differences seen for clinical outcomes in response to disease-modifying therapy
Timing of treatment start is an important predictor of disability accumulation in patients with pediatric-onset multiple sclerosis

Early Treatment Tied to Less Disability With Pediatric-Onset MS

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Less disability seen among those initiating disease-modifying therapy within two years of clinical onset
Comorbidities increase the rate of all-cause

Comorbidities Tied to Higher Rates of All-Cause Admissions in MS Patients

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But comorbidities not associated with increased hospitalizations related to multiple sclerosis
From 2011 to 2017

2011 to 2017 Saw Increase in Spending on DMTs for MS

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Increase in annual expenditures on MS DMTs mainly driven by increases in per-prescription costs