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Tag: Menopause / Postmenopause

Serum interleukin-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis

Serum IL-35 Levels Tied to Bone Loss With Rheumatoid Arthritis

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Low BMD, high bone metabolism, low vitamin D also seen in postmenopausal rheumatoid arthritis patients
Women with frequent or persistent vasomotor symptoms during the menopause transition have an increased risk for cardiovascular disease events

Vasomotor Symptoms in Women Tied to Higher Risk for CVD Events

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Frequent baseline VMS linked to higher risk for later CVD events; more visits also linked to CVD events
Testosterone can be used for postmenopausal women with hypoactive sexual desire dysfunction but is not recommended for other symptoms or medical conditions

Position Statement Clarifies Benefits of Testosterone Therapy for Women

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Testosterone only recommended for postmenopausal women with hypoactive sexual desire dysfunction
Use of menopausal hormone therapy is associated with an increased incidence of breast cancer

Type and Timing of Menopausal HRT Affect Risk for Breast Cancer

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Some excess risk persists for >10 years after ceasing therapy; magnitude varies with duration of use
Hormone therapy does not significantly impact muscle mass in postmenopausal women

Hormone Tx Not Tied to Change in Muscle Mass in Older Women

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No significant beneficial or detrimental association seen in postmenopausal women
For postmenopausal women with stable chest pain

Central Obesity Tied to CAD in Postmenopausal Chest Pain

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Central, but not overall, obesity linked to obstructive coronary artery disease underlying stable chest pain
Middle-aged women with type 2 diabetes mellitus have more sleep disturbances than women without diabetes

Type 2 Diabetes May Impact Sleep in Middle-Aged Women

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Findings show more sleep-related symptoms of symptoms of higher severity
Postmenopausal women with normoglycemia with a first-degree family history of diabetes have elevated bone mineral density

Family History of Diabetes Tied to Higher BMD in Normoglycemia

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Lumbar spine, femoral neck BMD higher in postmenopausal women with first-degree family history
The seeming association between parity and risk for type 2 diabetes among postmenopausal women is likely explained by adult weight gain

Adult Weight Gain Likely Explains Link Between Parity, T2DM Risk

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Risk for diabetes among postmenopausal women can be reduced by preventing adult weight gain
Hormone therapy formulations have differential effects on heart fat deposits in early menopausal women

Estrogen Preps Differ in Effects on Heart Fat Deposits

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Increase in epicardial adipose tissue less likely with oral conjugated equine estrogens in early menopause