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Certain Factors May Predict Weight Fluctuations After GLP-1 Receptor Agonist Treatment

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Longer treatment duration, using semaglutide, higher percentage body fat, and nondiabetic status may be associated with better weight reduction

Liraglutide May Reduce Migraine Burden in Adults With Obesity, Migraine

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Decrease seen in mean monthly headache days and reduction in Migraine Disability Assessment scores

ADA: Orforglipron Reduces Glycated Hemoglobin in Early Type 2 Diabetes

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All three doses of orforglipron superior to placebo with respect to primary end point of change in HbA1c from baseline to week 40

Likelihood of Psych Disorders Lower With Weight-Loss Surgery Versus GLP-1 RAs

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Lower risks for anxiety disorders, substance use disorders, cognitive deficits seen for those undergoing metabolic and bariatric surgery

Real-World Weight Loss With Semaglutide, Tirzepatide Less Than That Seen in Clinical Trials

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In real-world cohort, percentage weight reduction at one year was 3.6, 6.8, and 11.9 percent with early and late discontinuation and nondiscontinuation, respectively

GLP-1 Receptor Agonist Exposure Linked to Neovascular AMD in Patients With Diabetes

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More than twofold increased risk seen for nAMD development in unadjusted and adjusted models

ASCO: GLP-1 Receptor Agonists May Reduce Risk for Obesity-Related Cancer, All-Cause Death

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Protective association seen between GLP-1 receptor agonist use and colon and rectal cancers in adults with obesity and diabetes