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Tag: Liver Disease: Misc.

The U.S. Food and Drug Administration has received reports of rare cases of worsening liver function or liver failure in patients with chronic hepatitis C virus who had moderate-to-severe liver impairment and were treated with Mavyret

FDA Reports Rare Cases of Liver Injury, Failure With Hep C Therapies

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Worsening liver functioning, liver failure reported among patients contraindicated for HCV therapies
For women with intrahepatic cholestasis of pregnancy

Common Therapy for Obstetric Cholestasis Found Ineffective

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Treatment with ursodeoxycholic acid versus placebo yielded no significant difference in outcome
Living donor liver transplant offers superior outcomes and less resource utilization over deceased donor liver transplant

Superior Outcomes Seen for Living Donor Liver Transplant

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Living donor versus deceased donor liver transplant also yields less resource utilization
Type 2 diabetes mellitus is a risk factor for progression of liver fibrosis in patients with nonalcoholic fatty liver disease

T2DM Is Risk Factor for Liver Fibrosis Progression in NAFLD

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In multivariate analysis, age, albumin concentration, T2DM independently tied to progression

Digestive Disease Week, May 18-21

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Digestive Disease Week 2019 The annual Digestive Disease Week, sponsored by the American Association for the Study of Liver Diseases, American Gastroenterological Association,...
The risks for cirrhosis and hepatocellular carcinoma are increased for patients with a recorded diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Adverse Liver Outcomes Up With Diagnosis of NAFLD/NASH

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Baseline diagnosis of diabetes independent predictor of advanced liver disease diagnosis
The prevalence of alcoholic fatty liver disease has remained stable among U.S. adults

U.S. Prevalence of Alcoholic Fatty Liver Disease Stable at 4.7 Percent

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But prevalence of AFLD with stage 2 or greater fibrosis, AFLD with stage 3 or greater fibrosis increased
A considerable proportion of young adults have fibrosis and steatosis of the liver

Fibrosis, Steatosis of the Liver Observed in Some Young Adults

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Within Avon Longitudinal Study cohort, 2.4 percent of young adults had fibrosis; 20.8 percent had steatosis
Nonalcoholic fatty liver disease is becoming an increasingly important cause of liver disease and liver mortality among patients with HIV

Nonalcoholic Fatty Liver Disease Burden Up Among HIV-Infected

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NAFLD becoming increasingly important cause of liver disease, liver mortality
The risk of stillbirth is increased in women with intrahepatic cholestasis of pregnancy when serum bile acids concentrations are ≥100 µmol/L or more

Stillbirth Risk Up With High Serum Bile Acids in Pregnancy

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Higher risk of stillbirth with serum bile acids ≥100 µmol/L in intrahepatic cholestasis of pregnancy