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Tag: Inflammation

Treatment with ketoprofen may improve the skin biology in lymphedema

Pilot Studies May Shed Light on How to Treat Lymphedema

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Improvement in histopathology, skin thickness seen with ketoprofen in exploratory studies in humans
Magnetic resonance imaging positive for sacroiliitis is seen in a considerable number of healthy individuals without back pain

MRI Indicates Sacroiliitis in Some Healthy Individuals

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Considerable proportion of healthy individuals without back pain have MRI positive for sacroiliitis
Those with systemic inflammation during midlife are more likely to have age-related frailty

Systemic Inflammation at Midlife May Up Risk of Later Frailty

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Findings similar for composite scores of both C-reactive protein and four inflammatory markers
Ustekinumab improves psoriasis and reduces vascular inflammation among patients with moderate-to-severe psoriasis

AAD: Ustekinumab Cuts Vascular Inflammation in Psoriasis

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Reduction in total aortic vascular inflammation with ustekinumab versus increase with placebo
Acute myocardial infarction and chronic heart failure have effects on the brain

Brain Is Susceptible to Acute MI, Chronic Heart Failure

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Angiotensin-converting enzyme inhibitor treatment lowers acute inflammation in heart, brain
Soluble interleukin 2 receptor has slightly better diagnostic value than angiotensin-converting enzyme for sarcoidosis in patients with uveitis

Soluble Interleukin 2 Receptor IDs Sarcoidosis in Uveitis

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sIL-2R has slightly better diagnostic value than ACE for sarcoidosis in patients with uveitis
Most patients with immunoglobulin G subclass 4-related disease have increased levels of immunoglobulin E

Increases in IgE, Eosinophils, Mast Cells Can ID IgG4-RD

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Levels of IgE at diagnosis may be able to identify patients with IgG4-related disease, disease relapse
Ultrasonography findings seem to correlate well with the disease activity of idiopathic inflammatory myopathies

Ultrasound Findings Correlate With Inflammatory Myopathies

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While there is not a single ultrasound pattern, findings tied to disease activity
Data obtained from a pilot study

ENRGISE Pilot Study Will Inform Larger Trial of IL-6 in Seniors

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Pilot study expected to provide data on recruitment yields, feasibility, meds tolerance, adherence
Tocilizumab (Actemra) combined with a 26-week prednisone taper is superior to either 26-week or 52-week prednisone tapering plus placebo with regard to sustained glucocorticoid-free remission in patients with giant-cell arteritis

Tocilizumab Effective for Treatment of Giant-Cell Arteritis

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Longer follow-up called for to determine the durability of remission and safety