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Tag: Inflammation

Arthritis

ACR Previews New Pharmacotherapy Guidelines for RA

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The 2020 Guideline for the Management of Rheumatoid Arthritis updates guidance on drug treatments

COVID-19 may not cause a cytokine storm

Cytokines Not at ‘Storm’ Levels in Those With Severe COVID-19

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Levels in severely, critically ill COVID-19 patients much lower than in other inflammatory syndromes
Adult patients with current or previous severe acute respiratory syndrome coronavirus 2 can develop a hyperinflammatory syndrome

CDC Reports Cases of Multisystem Inflammatory Syndrome in Adults

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MIS-A related to SARS-CoV-2 infection resembles MIS in children; respiratory symptoms often minimal
There have been 792 confirmed cases in the United States of a rare condition in children that is linked to COVID-19

CDC: Nearly 800 U.S. Children Have Developed COVID-19-Related Condition

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Multisystem inflammatory syndrome in children also associated with 16 deaths reported in 42 states
Adding corticosteroids to initial intravenous immunoglobulin seems beneficial for preventing coronary artery abnormalities in high-risk patients with Kawasaki disease

Combination Therapy May Benefit Some With Kawasaki Disease

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Adding corticosteroids to initial IV immunoglobulin may reduce risk for coronary artery abnormalities
For patients with chronic edema of the leg and cellulitis

Compression Therapy Lowers Recurrence of Cellulitis of Leg

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Trial stopped early for efficacy in participants with chronic edema of the leg and recurrent cellulitis
As of July 29

CDC Updates Info on Multisystem Inflammatory Syndrome in Children

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Distinguishing this COVID-19-related syndrome from others can be challenging
Thyroid dysfunction in patients with psoriasis may be associated with inflammation caused by psoriasis

Inflammation Tied to Thyroid Dysfunction With Psoriasis

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Prevalence of thyroid dysfunction high with generalized pustular, erythrodermic psoriasis
Multisystem inflammatory syndrome in children

Multisystem Inflammatory Syndrome in Children Profiled

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Two reports describe characteristics of MIS-C seen in U.S. pediatric health centers, New York state
Children with COVID-19 may present with new neurological symptoms involving the central and peripheral nervous systems

Neurological Symptoms Described in Children With COVID-19

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Neurological symptoms involve central, peripheral nervous system; splenial changes ID'd on imaging