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Tag: Immunotherapy

COVID Vaccine Before ICI Initiation Tied to Increased Survival in Patients With Cancer

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SARS-CoV-2 mRNA vaccination within 100 days of ICI initiation was associated with increased overall survival in patients with NSCLC or metastatic melanoma

Recurrence-Free Survival Longer With Nivolumab Than Ipilimumab in Melanoma

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Median duration of recurrence-free survival was 61.1 months with nivolumab and 24.2 months with ipilimumab

Antithymocyte Globulin Cuts Loss of β-Cell Function in Type 1 Diabetes

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ATG 2.5 and 0.5 mg/kg reduces loss of β-cell function in young people with recent-onset type 1 diabetes

Stapokibart Found to Be Superior to Placebo for Severe Chronic Rhinosinusitis With Polyps

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Benefits include reduced polyp size and severity of nasal symptoms at 24 weeks

High Response to PD-1 Therapy Seen in Unresectable Desmoplastic Melanoma

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Complete response rate was 37 percent, and post-hoc end point of objective response rate was 89 percent

Sustained Clinical Benefit Seen for Pembrolizumab + Axitinib in Advanced Renal Cancer

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Sustained benefits seen in overall survival, progression-free survival, objective response rate with combo versus sunitinib

Patients With Leukemia Have Higher Infection Risk During Immunoglobulin Replacement Therapy

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Finding seen for patients with chronic lymphocytic leukemia receiving immunoglobulin replacement therapy regularly

Rituximab Not Superior to Conventional Strategy for Eosinophilic Granulomatosis With Polyangiitis

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Rituximab no better than glucocorticoids alone for inducing remission in patients with eosinophilic granulomatosis with polyangiitis

Guselkumab Efficacious for Moderately to Severely Active Crohn Disease in Adults

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Both guselkumab regimens superior to placebo

Presurgical Immunotherapy Offers Long-Term Benefit in Melanoma

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80 percent of adult patients with stage III/IV resectable melanoma remained event-free at four years from the start of neoadjuvant systemic treatment