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Tag: Immunotherapy

Outcomes With Immune Checkpoint Inhibitors Similar for Older, Younger Patients

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Older patients have divergent immune phenotypes at baseline that persist during immune checkpoint inhibitor therapy

AACR: Nonsurgical Treatment Feasible for Mismatch Repair-Deficient Tumors

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Neoadjuvant PD-1 blockade with dostarlimab enables nonoperative management strategy for large proportion of patients

Durable Disease Control Possible After Stopping Immune Checkpoint Inhibitors in NSCLC

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Predictors of longer postdiscontinuation progression-free survival include complete/partial response, longer treatment duration

AAAAI: Omalizumab Superior to Oral Immunotherapy in Multifood Allergy

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Most patients include dietary consumption of allergy-triggering foods after gaining tolerance

Peanut Oral Immunotherapy Yields Higher Rates of Tolerance in High-Threshold Allergy

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Significantly higher rates seen for desensitization, with durable response for home-measured peanut butter ingestion versus avoidance

TACE + Lenvatinib, Pembrolizumab Tied to Improved Survival in Unresectable Liver Cancer

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Clinically meaningful improvement seen in progression-free survival for transarterial chemoembolization plus lenvatinib and pembrolizumab

AI Can Reliably Predict Efficacy of Immune Checkpoint Inhibitor Therapy

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SCORPIO machine learning system can predict certain outcomes across diverse cancer types and health care settings

Black Patients Have Similar Immune Checkpoint Inhibitor Effectiveness, Lower Toxicity

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Black patients have longer time to treatment discontinuation, similar time to next treatment, slightly improved overall survival than White patients

Entinostat + Nivolumab Yields Durable Results in Some Pancreatic Cancer Patients

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Primary end point not met, but small subset of advanced pancreatic ductal adenocarcinoma patients showed durable responses

Adding Pembrolizumab Ups Survival in Stage III Undifferentiated Sarcoma

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Benefit seen for stage III undifferentiated pleomorphic sarcoma or dedifferentiated or pleomorphic liposarcoma of the extremity and limb girdles