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Tag: Immune Disorders

Lentiviral Gene Therapy Shows Sustained Clinical Efficacy for ADA-SCID

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Overall and event-free survival of 100 and 95 percent, respectively, seen with autologous CD34+ hematopoietic stem-cell lentiviral gene therapy

Researchers Win Nobel Prize for Uncovering How the Immune System Protects Itself

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The discovery has led to new treatments for autoimmune disorders, cancer and transplant recovery

FDA Grants Accelerated Approval for First Treatment for Barth Syndrome

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Forzinity helps improve strength of muscle to straighten the leg and works by improving mitochondria structure and function

Features of Immunesenescence Present in Early Stages of Rheumatoid Arthritis

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IMM-AGE score and other hallmarks of aging were raised in patients during early stages of rheumatoid arthritis

CVD Mortality Higher in Women Than Men With Immune-Mediated Inflammatory Diseases

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Decreases seen from 1999 to 2020 in both women and men, but mortality rates persistently higher for women

ACR: Inebilizumab Reduces Risk for Flares in IgG4-Related Disease

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Flare-free, treatment-free complete remission and flare-free, glucocorticoid-free complete remission improved with inebilizumab

Systemic Immune-Inflammation Index Tied to Mortality in CKD

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Association most pronounced for those older than 60 years and those with diabetes

Childhood Obesity Tied to Pediatric Immune-Mediated Skin Diseases

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Weight gain may increase atopic dermatitis risk, while weight loss may lower the risk

Algorithm From EHR Can ID Common Variable Immunodeficiency Disease

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74 percent of the top 100 patients ranked by PheNet were highly probable to have CVID

EEG Most Beneficial Tool for Managing CAR T-Cell-Related Neurotoxicity

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Therapeutic modification seen for 16 percent of patients with immune effector cell-associated neurotoxicity syndrome undergoing EEG