Tag: Hormone Replacement Therapy
SABCS: Breast Cancer Rates Opposite for Estrogen, Estrogen + Progestin
In postmenopausal women, breast cancer incidence down with estrogen alone, up with CEE + MPA
Age Modifies Effects of Estrogen Therapy in Women Without Ovaries
Women aged 50 to 59 years with BSO had treatment-associated decrease in all-cause mortality
Type and Timing of Menopausal HRT Affect Risk for Breast Cancer
Some excess risk persists for >10 years after ceasing therapy; magnitude varies with duration of use
Hormone Tx Not Tied to Change in Muscle Mass in Older Women
No significant beneficial or detrimental association seen in postmenopausal women
Premature Ovarian Insufficiency Tied to Poor Sleep Quality
Patients take longer to fall asleep, use more sleep aids, have more fatigue
Long-Term Systemic Hormone Therapy May Up Alzheimer Risk
Risk increases associated with hormone therapy exposure over 10 years in women <60 years at initiation
Cardiovascular Risk Increased During Gender Transition
Transwomen had higher incidence of strokes, VTEs than reference men and women
Prevalence of Knee OA Lower With Menopausal Hormone Therapy
Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model
Menopausal Hormone Tx Use Down Post-WHI Recommendations
But large declines seen in subgroups for whom MHT is recommended, including younger women
Transdermal HRT Not Linked to Increased Risk for VTE
But oral estrogen-only and combined hormone replacement tx tied to venous thromboembolism risk
