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Study Compares Benefits, Harms of Treatments for Chronic Hives

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Systematic review and network meta-analysis included 93 trials evaluating 42 interventions

FDA Approves Once-Monthly Andembry for Hereditary Angioedema

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The monoclonal antibody is a self-administered injection for prophylactic use to prevent attacks

Urticaria Reported in Trial of Investigational HIV mRNA Vaccines

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7 percent of 108 healthy volunteers reported urticaria; unresolved urticaria persisted at 12 months in four participants

FDA Approves Dupixent for Chronic Spontaneous Urticaria

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Approval granted for adults and children 12 years and older who remain symptomatic despite antihistamine treatment

Remibrutinib Beneficial for Urticaria After H1-Antihistamine Treatment

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Remibrutinib results in significant improvement in composite measure of itching and hives at week 12 after second-generation H1-antihistamine treatment

ACAAI: Gene-Editing Therapy Reduces Angioedema Attacks in Hereditary Angioedema

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Reduction of 75 and 77 percent seen in estimated mean monthly attack rate with 25-mg, 50-mg NTLA-2002 versus placebo

Acupuncture Offers Some Benefit in Chronic Spontaneous Urticaria

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However, differences between acupuncture and sham acupuncture, wait-list control did not meet threshold for minimal clinically important difference

Ligelizumab appears to be a safe and effective treatment option for chronic spontaneous urticaria

Ligelizumab Safely, Effectively Treats Hives

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Doses of 72 mg or 240 mg tied to complete control of symptoms after 12-week trial
Omalizumab

Omalizumab Effective for Chronic Spontaneous Urticaria

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In small study, 85 percent of refractory CSU patients had complete response; rest had well-controlled dx
HIV-infected and HIV-exposed but uninfected children have lower cognitive and motor scores than HIV-unexposed and uninfected children

Review: Lower Cognitive Scores for HIV+, HIV-Exposed Children

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Lower scores for HIV+, HIV-exposed uninfected children versus HIV-unexposed and uninfected