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A toll-like receptor 9 agonist in the presence of alum is stable over a month and elicits strong anti-heroin antibody titers and blockade of heroin-induced antinociception

Anti-Heroin Vaccine Shows Promise Against Lethal Doses

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TLR9 agonist in presence of alum is stable over 30 days, elicits strong anti-heroin antibody titers
Q-switched Nd:YAG 1064 nm laser treatment may be beneficial for treating linear hyperpigmented streaks on the bilateral forearms

Q-Switched Nd:YAG 1064 nm Laser Can Improve Track Marks

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Case report describes improvement in bluish-gray pigmentation in patient with history of heroin use
Extended-release naltrexone is noninferior to buprenorphine-naloxone for maintaining short-term abstinence from heroin and other illicit substances

Extended-Release Naltrexone Promising for Opioid Dependence

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Lower use of heroin, other illicit opioids with extended-release naltrexone in superiority analysis
Prescription opioid-related inpatient and emergency department discharges have decreased since 2010

Hospital Discharges for Prescription Opioids Have Fallen

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But inpatient and ED discharges related to heroin have increased in past decade
From 2001-2002 to 2012-2013 there was an increase in the prevalence of heroin use and heroin use disorder

Increases in Heroin Use in the U.S. Greater Among Whites

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Increase in prevalence of heroin use, heroin use disorder, with increase more pronounced in whites
Young adults in the United States are more likely to become addicted to prescription opioids than they were in years past

Opioid Use Disorder, Heroin Use Up Among Young Adults

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Study also finds abuse of opioids often precedes heroin use
Hydromorphone may be another treatment option for heroin addiction

Hydromorphone May Be New Treatment for Heroin Addiction

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Researchers find hydromorphone an effective, widely available, licensed choice
U.S. researchers are challenging a leading theory about the nation's heroin epidemic

Pathway to Heroin Described in NEJM Commentary

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Initial exposure to opioids appears to 'push' potential addicts to heroin
Concurrent use of heroin and prescription opioids is increasing

More Prescription Opioid Addicts Are Turning to Heroin

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Interviews with addicts confirm desire for cheaper, more plentiful substitute
Allowing more emergency medical service workers to administer the prescription drug naloxone could reduce the number of overdose deaths caused by opioids

CDC: Expanding EMS Naloxone Use Will Save Lives

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CDC urges expansion of access to the prescription antidote among EMS personnel