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Researchers have released yet another study finding impressive results for an experimental drug combo that aims to rid the body of hepatitis C. The study is published in the May 5 issue of the Journal of the American Medical Association.

Experimental Drug Combo Shows Success in HCV Treatment

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Drug trio could join newer, highly-effective meds such as sofosbuvir, ledipasvir/sofosbuvir
Prednisolone and pentoxifylline are associated with limited and no benefits

Prednisolone, Pentoxifylline Little Use in Alcoholic Hepatitis

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Nonsignificant drop in 28-day mortality with prednisolone; no improvement with pentoxifylline
For patients with hepatitis C virus

Statin Use Found Beneficial in Hepatitis C Treatment

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Improved virologic response rates, decreased liver fibrosis progression, HCC incidence
Preliminary lab research suggests the antihistamine chlorcyclizine HCl that costs about 50 cents a pill has the potential to treat hepatitis C

Inexpensive Antihistamine Repurposed to Focus on HCV

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Lab tests suggest over-the-counter antihistamine could offer alternative to pricey new drugs
Symptomatic bradycardia can occur when amiodarone is taken with new hepatitis C medications

FDA Warns Against Amiodarone Use With Hepatitis C Meds

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Adding ledipasvir/sofosbuvir or sofosbuvir to amiodarone could cause symptomatic bradycardia
Kidney transplant patients with HIV have similar survival rates as those without HIV

Outcomes Favorable for HIV+ Kidney Transplant Recipients

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However, survival rates lower if organ recipient also has hepatitis C
A vaccine for hepatitis E provides protection from the virus for at least 4.5 years

Vaccine May Provide Some Protection From Hepatitis E

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Immunization offers nearly five years of protection, researchers say
The prevalence of unrecognized chronic hepatitis C virus is high among baby boomers presenting to the emergency department

High Prevalence of HCV in Baby Boomers Presenting to ER

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Unrecognized HCV more likely among males, African-Americans, under/uninsured patients
Two cases of hepatitis C infection that occurred during routine surgeries highlight the need for hospitals to tighten infection control to prevent more transmissions

CDC: Routine Procedures Lead to Two Cases of HCV Transmission

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In both cases, there were breaches in safety rules, CDC reports
For patients with hepatitis C virus genotype 1 and HIV coinfection

SVR Rates Up With New Regimens for HCV and HIV Coinfection

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Studies show high rates for all-oral, interferon-free 3D plus ribavirin regimen, ledipasvir + sofosbuvir