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For older patients with hepatitis C virus

Direct-Acting Antivirals Effective for Hepatitis C in Seniors

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Increased likelihood of adverse events, anemia secondary to ribavirin for those age 75 or older
Post-transplant hepatitis C treatment increases access to transplant and reduces waitlist time among hepatitis C-positive patients awaiting kidney transplantation

Post-Transplant Tx Reduces Wait for Kidney in Hep C+ Patients

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Delaying treatment until after transplant doesn't adversely impact kidney allograft or survival
Many infants who are exposed to hepatitis C virus (HCV) during pregnancy are not screened for HCV infection

Hepatitis C-Exposed Infants Not Adequately Screened

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Low screening rate seen at same time as increase in hepatitis C virus prevalence among pregnant women
A novel purchasing strategy could dramatically reduce the costs of medications for hepatitis C virus

Novel Purchasing Strategy Could Cut Medicaid Costs for HCV Meds

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Strategy involves making deal with manufacturer for a lump-sum payment in return for 100 percent rebate
Sofosbuvir-based treatment appears to guarantee renal safety for patients with chronic hepatitis C virus over one year of follow-up

Sofosbuvir Improves Renal Safety in Patients With Chronic Hep C

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Patients with mild, moderate renal impairment showed improvement in renal biomarkers over one year
Metabolic syndrome is prevalent among patients with chronic hepatitis B infection

Metabolic Syndrome Common With Chronic Hep B Infection

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Metabolic syndrome also associated with higher alanine aminotransferase levels longitudinally
For baby boomers

Hepatitis C Screening Increasing Among Baby Boomers

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Screening prevalence 11.5 to 12.8 percent; similar rate for cohort born from 1966 to 1985
For patients with chronic hepatitis B virus

BMI Linked to Hepatocellular Carcinoma Risk in Chronic Hep B

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Risk of HCC linked to BMI in a dose-response manner in men, women; stronger link for women
Alcohol dependence has deleterious effects on frontal cortical volumes that are compounded by hepatitis C virus infection and drug dependence

Hep C Compounds Alcoholism’s Effect on Brain Volume

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Deleterious effect of alcohol dependence on frontal cortical volumes also compounded by drug use
Maternal use of tenofovir disoproxil fumarate in addition to administration of hepatitis B immune globulin and hepatitis B vaccine to infants born to hepatitis B e antigen-positive pregnant women does not further lower the rate of hepatitis B virus transmission

Maternal Use of TDF Doesn’t Further Reduce HBV Transmission

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Findings in setting with low HBV transmission with administration of hepatitis B immune globulin, vaccine