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Mavyret (glecaprevir and pibrentasvir) tablets are now approved to treat all six genotypes of hepatitis C virus in children ages 12 to 17 years

FDA Approves Mavyret for Children, Adolescents With Hep C

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Drug approved for treatment of all six genotypes of hepatitis C virus in children ages 12 to 17
For people with hepatitis C virus who inject drugs and receive opioid agonist therapy

High Response Seen for All Hep C Tx Models in Injection Drug Users

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Directly observed therapy tied to greater adherence than self-administered individual treatment
Hearts and lungs from donors with hepatitis C viremia can be safely transplanted into patients without hepatitis C virus infection

Heart, Lungs From Hep C-Infected Donor Can Be Transplanted Safely

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Transplant into patients without HCV infection feasible, with excellent function at six months
The outcomes of kidney transplants in patients with viral suppression are as good as those for kidney transplants in patients not infected with hepatitis B virus or hepatitis C virus

HBV, HCV Control Aids Kidney Transplant Outcomes

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Patients with viral suppression have outcomes similar to those of noninfected patients
For adults with chronic hepatitis C virus infection

Direct-Acting Antivirals Cut Mortality in Chronic Hepatitis C

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Mortality, hepatocellular carcinoma risk reduced after adjustment for potential confounders
States with above-median OxyContin misuse before reformulation of the drug experienced a 222 percent increase in hepatitis C infection rates after reformulation

Hepatitis C Infection Rates Up After OxyContin Reformulation

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222 percent increase in HCV infection rates seen after reformulation in states with above-median misuse
Public health interventions can go a long way toward meeting World Health Organization hepatitis C virus targets

Public Health Interventions Could Cut Global Burden of Hepatitis C

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Package of prevention, screening, treatments could avert 15.1 million new infections versus 2015
Direct-acting antiviral therapy is not associated with increased overall or early hepatocellular carcinoma (HCC) recurrence among patients with a previous complete response to HCC treatment

Direct-Acting Antivirals Not Tied to Liver Cancer Recurrence

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Among patients with previous complete response to HCC tx, DAA not linked to overall or early recurrence
Among deceased organ donors

CDC: Proportion of Increased-Risk Deceased Organ Donors on Rise

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Increased-risk donors significantly more likely to have positive HBV, HCV screening results
A substantial proportion of patients with newly diagnosed cancer and concurrent hepatitis B virus or hepatitis C virus infection are unaware of their viral infection at the time of cancer diagnosis

Many New Cancer Patients Unaware of Their Hepatitis Status

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Large proportion of participants with newly diagnosed cancer learned of infection through study