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Tag: Heart / Stroke-Related: High Cholesterol

Higher triglycerides is associated with a decreased risk of cognitive decline

Higher Triglycerides May Be Protective in the Very Elderly

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Higher triglyceride levels tied to lower risk of cognitive decline, ADL decline, frailty aggravation, and death
For patients with a recent acute coronary syndrome receiving a statin

Price of Alirocumab Would Have to Be Cut to Be Cost-Effective

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Price of alirocumab would have to decrease from original cost of $14,560 to $1,974 to be cost-effective
Adherent patients receiving high-intensity statin and/or ezetimibe therapy have the lowest cardiovascular risk

Adherence and Intensity of Lipid-Lowering Tx Influence CV Risk

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Lowest risk seen for adherent patients receiving high-intensity statin and/or ezetimibe regimen
Less than an hour a week of resistance exercise is associated with decreased risks for cardiovascular disease-related events and all-cause mortality

Less Than One Hour of Resistance Training Weekly Tied to Lower CVD Risk

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No further risk reduction for CVD morbidity, all-cause mortality seen for ≥60 minutes/week
A healthy lifestyle for lowering cholesterol should be emphasized for reducing cardiovascular risk across the life course

AHA: Guidelines Stress Healthy Lifestyle for Lowering Cholesterol

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LDL-C should be reduced with high-intensity or maximally tolerated statin therapy
Intensive blood pressure control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events

ASN: Aggressive Control of BP, Lipids in T2DM May Up Kidney Risk

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Strict BP control, fenofibrate use may increase long-term risk for adverse kidney events in T2DM patients
Genetic testing should become the standard of care for patients with definite or probable familial hypercholesterolemia

Genetic Testing Recommended for Familial Hypercholesterolemia

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Expert panel recommends genetic testing as standard of care for definite or probable cases
Low-density lipoprotein cholesterol and non-high density lipoprotein cholesterol ≥160 mg/dL are independently associated with increased relative risk of cardiovascular disease mortality in a low-risk cohort

High LDL in Young, Healthy Adults Leaves Them Vulnerable to CVD

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Findings may have implications for future cholesterol treatment paradigms
Elevated high-density lipoprotein cholesterol may not always be cardioprotective in postmenopausal women

‘Good’ Cholesterol May Not Be So in Postmenopausal Women

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High total HDL cholesterol in postmenopausal women may mask heart disease risk
There has been a substantial increase in the percentage of patients with high cholesterol over age 60 years taking lipid-lowering medications from 2005 to 2016

CDC: More People With High Cholesterol Taking Medications

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Findings only among men and women over 60 years, not younger patients with high cholesterol