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Tag: Heart / Stroke-Related: High Cholesterol

Replacing saturated fats with polyunsaturated fats and monounsaturated fats can reduce cardiovascular disease risk as much as statins

Replacing Saturated Fats With Healthy Fats Lowers CVD Risk

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Healthy fats can help reduce risk of cardiovascular disease as effectively as statins, researchers say
Two separate research groups say they've successfully reduced cholesterol in humans by using different methods to block the angiopoietin-like 3 (ANGPTL3) gene. The findings were published online May 24 in the New England Journal of Medicine.

Targeting ANGPTL3 Can Significantly Lower Cholesterol

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Two trials show promise for non-statin approach to cardiovascular disease prevention
The prevalence of elevated cardiovascular risk is low in normotensive

Findings Support More Targeted Approach to Cholesterol Screens

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Among normotensive nonsmokers without diabetes, very few at heightened risk of ASCVD
Many patients report lack of confidence or knowledge in keeping cholesterol under control

AHA: Patients Lack Confidence in Managing Their Cholesterol

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Patients feel least informed about target body weight, types of cholesterol, goals for management
Evolocumab and inclisiran

ACC: Meds Targeting PCSK9 Show Benefit for High-Risk Patients

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Evolocumab and inclisiran inhibit proprotein convertase subtilisin-kexin type 9
For patients undergoing arthroscopic rotator cuff repair

AAOS: Cholesterol, LDL Impact Rotator Cuff Repair Revision

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Statins mitigate this effect, with revision rates not significantly different for patients prescribed statins
Cholesterol's impact on myocardial infarction may differ by age

ACC: Younger MI Patients More Likely to Have Low HDL, High LDL

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Different measures may be required to accurately identify MI risk in this age group
For women with early-stage

Cholesterol Lowering Rx Cuts Recurrence in Breast Cancer

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Initiation of CLM during endocrine tx tied to improved disease-free survival, recurrence-free intervals
For youth with type 1 diabetes

HbA1c, Waist-to-Height Ratio Predict Dyslipidemia in T1DM

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For youth with type 1 diabetes, hemoglobin A1c and waist-to-height ratio are modifiable risk factors
The cholesterol-lowering supplement red yeast rice could pose the same health risks to users as statin drugs

Safety Profile of Red Yeast Rice Found Similar to Statins

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The supplements linked to myalgias, other adverse effects similar to statins