Tag: Genetics
MTHFR Polymorphism, Higher Homocysteine Up Cataract Risk
Increased risk for methylenetetrahydrofolate reductase polymorphism, elevated homocysteine
Familial Hypercholesterolemia More Common Than Thought
Researchers find roughly 834,500 Americans have inherited condition
CYP3A7*1C Allele Linked to Cancer Mortality, Progression
Associated with adverse outcomes in breast cancer, lung cancer, chronic lymphocytic leukemia
Gene Test IDs Breast CA Patients Who May Not Need Chemo
Analysis can help women who won't benefit from additional treatment to avoid side effects
Large Number of Mutations Needed to ID TB Drug Resistance
Predicted resistance to rifampicin and isoniazid ID'd based on 238 mutations across 18 genetic loci
ACOG Issues Recommendations on Prenatal Screening
Bulletins relate to prenatal diagnostic testing for genetic disorders, screening for fetal aneuploidy
Mutations in ANGPTL4 Linked to Coronary Artery Disease
Two studies show variant carriers have better lipid levels, lower likelihood of coronary artery disease
PRAME Predicts Metastasis in Class 1 Uveal Melanoma
PRAME mRNA expression is independent prognostic biomarker in Class 1 uveal melanoma
Many Do Not Share Personal Genetic Testing Results With PCP
Reasons for not sharing include that the results are not important enough, lack of time
New Mutations Help Predict Survival in RARS-T
Mutations help classify risk in refractory anemia with ring sideroblasts and thrombocytosis
