Tag: Genetics
Danazol Treatment Linked to Telomere Elongation
Reduction in rate of telomere attrition at 24 months; gain in telomere length seen from six months
ASCO: Phase I Cancer Drug Trials Benefit From Precision Medicine
Better outcomes for patients whose treatment is selected based on molecular characteristics of tumor
Skeletal Muscle TRIB3 Mediates Diet-Induced Insulin Resistance
TRIB3 overexpressing mice have greater weight gain, worse insulin resistance in response to high-fat diet
ASGR1 Mutation Linked to Reduced Levels of Non-HDL-C
Heterozygous mutation carriers have lower levels of non-HDL-C, reduced risk of coronary artery disease
Neuronal GHS-R Involved in Regulating Energy Metabolism
Deletion of neuronal Ghsr in mice almost completely prevents diet-induced obesity
Genetic Variants ID Treatment Response in Psoriasis
Ten SNPs presented that correlate with treatment responses to anti-TNF-α agents
AUA: BRCA Mutations May Play Role in Prostate Cancer
Multiple studies suggest they might
Adiposity Genetic Risk Score Tied to Cardiometabolic Health
Genetic risk score from 11 variants linked to lower risk of type 2 diabetes, hypertension, heart disease
MAGED2 Mutation Causes Antenatal Bartter’s Syndrome
Symptoms disappeared spontaneously during follow-up in infants who survived
FDA Panel Votes Against Approval of Eteplirsen for DMD
Clinical data did not meet the agency's requirements for well controlled studies necessary for approval
